Forsythiaside inhibits bacterial adhesion on titanium alloy and attenuates Ti-induced activation of nuclear factor-κB signaling-mediated macrophage inflammation

Forsythiaside inhibits bacterial adhesion on titanium alloy and attenuates Ti-induced activation of nuclear factor-κB signaling-mediated macrophage inflammation

Abstract Background Inflammation and biofilm formation by Staphylococcus aureus (S. aureus) are common causes of periprosthetic infection and loosening. Recently, we identified that forsythiaside is bacteriostatic for S. aureus and methicillin-resistant S. aureus (MRSA). The purpose of the present s...

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Bibliographic Details
Main Authors: Haifeng Li, Dongmei Tang, Chao Qi, Xia Zhao, Guangchao Wang, Yi Zhang, Tengbo Yu
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Titanium
Forsythiaside
Anti-bacteria
Anti-inflammation
Nuclear factor-κB signaling pathway
Online Access:http://link.springer.com/article/10.1186/s13018-018-0834-x

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http://link.springer.com/article/10.1186/s13018-018-0834-x

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