Microfluidic synthesis of fibronectin-coated polydopamine nanocomplexes for self-supplementing tumor microenvironment regulation and MR imaging-guided chemo-chemodynamic-immune therapy

Microfluidic synthesis of fibronectin-coated polydopamine nanocomplexes for self-supplementing tumor microenvironment regulation and MR imaging-guided chemo-chemodynamic-immune therapy

Development of nanomedicines to overcome the hindrances of tumor microenvironment (TME) for tumor theranostics with alleviated side effects remains challenging. We report here a microfluidic synthesis of artesunate (ART)-loaded polydopamine (PDA)/iron (Fe) nanocomplexes (NCs) coated with fibronectin...

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Bibliographic Details
Main Authors: Rui Yang, Mengsi Zhan, Zhijun Ouyang, Honghua Guo, Jiao Qu, Jindong Xia, Mingwu Shen, Xiangyang Shi
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Materials Today Bio
Subjects:
Polydopamine iron nanocomplex
Microfluidic synthesis
Tumor microenvironment regulation
Enhanced chemodynamic therapy
Immune checkpoint blockade
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423001308

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