Analysis of the drug treatment in patients with stable coronary artery disease before and after surgical myocardial revascularization
The aim – to analyze the drug treatment of patients with stable CAD before and after coronary artery bypass grafting (CABG), to study the potential possibilities of usage of the contemporary pharmacotherapeutic technologies to improve treatment adherence of the patients. Materials and methods. The...
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| Format: | Article |
| Language: | English |
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TOV Chetverta Khvylia
2019-03-01
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| Series: | Кардіохірургія та інтервенційна кардіологія |
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| Online Access: | http://csic.com.ua/images/pdf/2019/1-2019/analysis-drug-treatment-patients-with-stable-coronary-artery-disease.pdf |
| _version_ | 1826840182149611520 |
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| author | О.J. Zharinov О.А. Yepanchintseva К.O. Mikhaliev I.V. Shklianka |
| author_facet | О.J. Zharinov О.А. Yepanchintseva К.O. Mikhaliev I.V. Shklianka |
| author_sort | О.J. Zharinov |
| collection | DOAJ |
| description | The aim – to analyze the drug treatment of patients with stable CAD before and after coronary artery bypass grafting (CABG), to study the potential possibilities of usage of the contemporary pharmacotherapeutic technologies to improve treatment adherence of the patients.
Materials and methods. The one-centre cross-sectional study analyzed data regarding treatment of 155 patients with stable CAD that had consecutive CABG performed in 2012–2013, before, peri- and after surgery. Among these patients there were 139 men and 16 women, age 39–81 years, median age 62 (quartiles 55–67) years. In 134 (86.4 %) patients on-pump myocardial revascularization was performed.
Results. Peri- and after surgery treatment in vast majority of cases included standard basic drugs recommended for stable CAD. At the same time, we paid attention to the insufficient usage of statins. I.e., high-intensity treatment with statins during one week before surgery was prescribed only in 19 (12.2 %) patients. The routine usage of dual antiplatelet therapy in nearly 95 % patients with stable CAD after elective CABG also didn’t completely correspond to the current guidelines.
Conclusions. The performed analysis shows real possibilities of better correspondence to the current guidelines and patients’ adherence to the treatment in case of usage of the contemporary combined drug forms, including the «polypill» technology. |
| first_indexed | 2024-04-13T22:11:56Z |
| format | Article |
| id | doaj.art-72bdefbab6e44eec9418eef000d0b8b9 |
| institution | Directory Open Access Journal |
| issn | 2305-3127 |
| language | English |
| last_indexed | 2025-02-16T12:37:02Z |
| publishDate | 2019-03-01 |
| publisher | TOV Chetverta Khvylia |
| record_format | Article |
| series | Кардіохірургія та інтервенційна кардіологія |
| spelling | doaj.art-72bdefbab6e44eec9418eef000d0b8b92025-02-03T00:35:06ZengTOV Chetverta KhvyliaКардіохірургія та інтервенційна кардіологія2305-31272019-03-011142010.31928/2305-3127-2019.1.1420Analysis of the drug treatment in patients with stable coronary artery disease before and after surgical myocardial revascularizationО.J. Zharinov0О.А. Yepanchintseva1К.O. Mikhaliev2I.V. Shklianka3Shupyk National Medical Academy of Postgraduate Education, Kyiv, UkraineShupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Heart Institute, Ministry of Health of Ukraine, Kyiv, UkraineState Scientific Institution «Scientific and Practical Center of Preventive and Clinical Medicine» State Government Affairs, Kyiv, UkraineShupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Heart Institute, Ministry of Health of Ukraine, Kyiv, UkraineThe aim – to analyze the drug treatment of patients with stable CAD before and after coronary artery bypass grafting (CABG), to study the potential possibilities of usage of the contemporary pharmacotherapeutic technologies to improve treatment adherence of the patients. Materials and methods. The one-centre cross-sectional study analyzed data regarding treatment of 155 patients with stable CAD that had consecutive CABG performed in 2012–2013, before, peri- and after surgery. Among these patients there were 139 men and 16 women, age 39–81 years, median age 62 (quartiles 55–67) years. In 134 (86.4 %) patients on-pump myocardial revascularization was performed. Results. Peri- and after surgery treatment in vast majority of cases included standard basic drugs recommended for stable CAD. At the same time, we paid attention to the insufficient usage of statins. I.e., high-intensity treatment with statins during one week before surgery was prescribed only in 19 (12.2 %) patients. The routine usage of dual antiplatelet therapy in nearly 95 % patients with stable CAD after elective CABG also didn’t completely correspond to the current guidelines. Conclusions. The performed analysis shows real possibilities of better correspondence to the current guidelines and patients’ adherence to the treatment in case of usage of the contemporary combined drug forms, including the «polypill» technology.http://csic.com.ua/images/pdf/2019/1-2019/analysis-drug-treatment-patients-with-stable-coronary-artery-disease.pdfstable coronary artery diseasecoronary artery bypass graftingdrug treatment |
| spellingShingle | О.J. Zharinov О.А. Yepanchintseva К.O. Mikhaliev I.V. Shklianka Analysis of the drug treatment in patients with stable coronary artery disease before and after surgical myocardial revascularization Кардіохірургія та інтервенційна кардіологія stable coronary artery disease coronary artery bypass grafting drug treatment |
| title | Analysis of the drug treatment in patients with stable coronary artery disease before and after surgical myocardial revascularization |
| title_full | Analysis of the drug treatment in patients with stable coronary artery disease before and after surgical myocardial revascularization |
| title_fullStr | Analysis of the drug treatment in patients with stable coronary artery disease before and after surgical myocardial revascularization |
| title_full_unstemmed | Analysis of the drug treatment in patients with stable coronary artery disease before and after surgical myocardial revascularization |
| title_short | Analysis of the drug treatment in patients with stable coronary artery disease before and after surgical myocardial revascularization |
| title_sort | analysis of the drug treatment in patients with stable coronary artery disease before and after surgical myocardial revascularization |
| topic | stable coronary artery disease coronary artery bypass grafting drug treatment |
| url | http://csic.com.ua/images/pdf/2019/1-2019/analysis-drug-treatment-patients-with-stable-coronary-artery-disease.pdf |
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