Characteristics of Teenagers Presenting with Chest Pain after COVID-19 mRNA Vaccination
In this study, we evaluated the clinical and radiological manifestations of teenagers presenting with chest pain after coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccination. We retrospectively enrolled 61 teenage patients, aged 13 to 19 years, who underwent echocardiography and cardia...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/13/4421 |
| _version_ | 1797591417443319808 |
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| author | Chul Hwan Park Juyeon Yang Hye Sun Lee Tae Hoon Kim Lucy Youngmin Eun |
| author_facet | Chul Hwan Park Juyeon Yang Hye Sun Lee Tae Hoon Kim Lucy Youngmin Eun |
| author_sort | Chul Hwan Park |
| collection | DOAJ |
| description | In this study, we evaluated the clinical and radiological manifestations of teenagers presenting with chest pain after coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccination. We retrospectively enrolled 61 teenage patients, aged 13 to 19 years, who underwent echocardiography and cardiac magnetic resonance imaging (CMR) for chest pain after COVID-19 mRNA vaccination, from November 2021 to April 2022. Medical records, laboratory results, echocardiographic, and CMR findings were analyzed. The mean age of the participants was 14.4 ± 1.9 years, with a male:female ratio of 28:33. Among the sixty-one patients with chest pain after COVID-19 vaccination, only two (3.3%) were diagnosed as confirmed myocarditis, and almost all of them recovered with conservative treatments. However, on CMR, 24 (39.3%) presented with mild myocardial abnormalities; 22 (36.1%) showed myocardial edema, and 19 (31.1%) were found to have a myocardial injury. Multivariate logistic analyses revealed that older age and female sex were significantly associated with myocardial abnormalities. In teenagers who present with chest pain after COVID-19 mRNA vaccination, confirmed myocarditis is uncommon. However, myocardial abnormalities on CMR might occur frequently, and females in their late teens might be more vulnerable to myocardial abnormalities. |
| first_indexed | 2024-03-11T01:37:08Z |
| format | Article |
| id | doaj.art-72c0654e014643e1a3584a01465d8026 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T01:37:08Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-72c0654e014643e1a3584a01465d80262023-11-18T16:53:39ZengMDPI AGJournal of Clinical Medicine2077-03832023-06-011213442110.3390/jcm12134421Characteristics of Teenagers Presenting with Chest Pain after COVID-19 mRNA VaccinationChul Hwan Park0Juyeon Yang1Hye Sun Lee2Tae Hoon Kim3Lucy Youngmin Eun4Department of Radiology and Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of KoreaBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaDepartment of Radiology and Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of KoreaDepartment of Pediatrics, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of KoreaIn this study, we evaluated the clinical and radiological manifestations of teenagers presenting with chest pain after coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccination. We retrospectively enrolled 61 teenage patients, aged 13 to 19 years, who underwent echocardiography and cardiac magnetic resonance imaging (CMR) for chest pain after COVID-19 mRNA vaccination, from November 2021 to April 2022. Medical records, laboratory results, echocardiographic, and CMR findings were analyzed. The mean age of the participants was 14.4 ± 1.9 years, with a male:female ratio of 28:33. Among the sixty-one patients with chest pain after COVID-19 vaccination, only two (3.3%) were diagnosed as confirmed myocarditis, and almost all of them recovered with conservative treatments. However, on CMR, 24 (39.3%) presented with mild myocardial abnormalities; 22 (36.1%) showed myocardial edema, and 19 (31.1%) were found to have a myocardial injury. Multivariate logistic analyses revealed that older age and female sex were significantly associated with myocardial abnormalities. In teenagers who present with chest pain after COVID-19 mRNA vaccination, confirmed myocarditis is uncommon. However, myocardial abnormalities on CMR might occur frequently, and females in their late teens might be more vulnerable to myocardial abnormalities.https://www.mdpi.com/2077-0383/12/13/4421COVID-19vaccinationmRNAchest painmyocarditisechocardiography |
| spellingShingle | Chul Hwan Park Juyeon Yang Hye Sun Lee Tae Hoon Kim Lucy Youngmin Eun Characteristics of Teenagers Presenting with Chest Pain after COVID-19 mRNA Vaccination Journal of Clinical Medicine COVID-19 vaccination mRNA chest pain myocarditis echocardiography |
| title | Characteristics of Teenagers Presenting with Chest Pain after COVID-19 mRNA Vaccination |
| title_full | Characteristics of Teenagers Presenting with Chest Pain after COVID-19 mRNA Vaccination |
| title_fullStr | Characteristics of Teenagers Presenting with Chest Pain after COVID-19 mRNA Vaccination |
| title_full_unstemmed | Characteristics of Teenagers Presenting with Chest Pain after COVID-19 mRNA Vaccination |
| title_short | Characteristics of Teenagers Presenting with Chest Pain after COVID-19 mRNA Vaccination |
| title_sort | characteristics of teenagers presenting with chest pain after covid 19 mrna vaccination |
| topic | COVID-19 vaccination mRNA chest pain myocarditis echocardiography |
| url | https://www.mdpi.com/2077-0383/12/13/4421 |
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