Interferon-Alpha Decreases Cancer Stem Cell Properties and Modulates Exosomes in Malignant Melanoma

Interferon-Alpha Decreases Cancer Stem Cell Properties and Modulates Exosomes in Malignant Melanoma

Malignant melanoma (MM) can spread to other organs and is resistant in part due to the presence of cancer stem cell subpopulations (CSCs). While a controversial high dose of interferon-alpha (IFN-α) has been used to treat non-metastatic high-risk melanoma, it comes with undesirable side effects. In...

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Bibliographic Details
Main Authors: María Belén García-Ortega, Ernesto Aparicio, Carmen Griñán-Lisón, Gema Jiménez, Elena López-Ruiz, José Luis Palacios, Gloria Ruiz-Alcalá, Cristina Alba, Antonio Martínez, Houria Boulaiz, Macarena Perán, Michael Hackenberg, José Bragança, Sofia M. Calado, Juan A. Marchal, María Ángel García
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
interferon-α
malignant melanoma
cancer stem cells
exosomes
metabolomics
biomarkers
Online Access:https://www.mdpi.com/2072-6694/15/14/3666

Internet

https://www.mdpi.com/2072-6694/15/14/3666

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