Phenotypes of patients with chronic obstructive pulmonary disease
Aim. To study characteristics of phenotypes of chronic obstructive pulmonary disease (COPD) basing on the findings of modern clinical, functional and roentgenomorphological tests in the course of the disease. Material and methods. Basing on the results of high performance computed tomography, 64 COP...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2009-03-01
|
| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/30272 |
| _version_ | 1828417229764427776 |
|---|---|
| author | A V Aver'yanov A G Chuchalin A E Polivanova G E Polivanov A V Chernyak G V Neklyudova Zh K Naumenko A V Averianov A G Chuchalin A E Polivanova G E Polivanov A V Chernyak G V Neklyudova Zh K Naumenko |
| author_facet | A V Aver'yanov A G Chuchalin A E Polivanova G E Polivanov A V Chernyak G V Neklyudova Zh K Naumenko A V Averianov A G Chuchalin A E Polivanova G E Polivanov A V Chernyak G V Neklyudova Zh K Naumenko |
| author_sort | A V Aver'yanov |
| collection | DOAJ |
| description | Aim. To study characteristics of phenotypes of chronic obstructive pulmonary disease (COPD) basing on the findings of modern clinical, functional and roentgenomorphological tests in the course of the disease.
Material and methods. Basing on the results of high performance computed tomography, 64 COPD patients aged 46-75 years (FEV1 51 ± 24%) were divided into two groups: 53 patients with emphysematous phenotype (group 1) and 11 patients with bronchytic phenotype (group 2). The groups were compared by constitutional, clinical, functional and roentgenological parameters.
Results. Group 1 patients had significantly less body mass index, more severe edema by Borg's scale, low FEV1, FEV1/FLC, diffuse lung capacity and lung tissue density compared to group 2. Bronchoectases occurred more frequently in group 1 (33 and 9%, respectively).
Conclusion. Heterogenous COPD phenotypes differ not only at the stage of chronic respiratory insufficiency but also at all stages of the disease. |
| first_indexed | 2024-12-10T14:16:49Z |
| format | Article |
| id | doaj.art-72c51deafd9a46e2b867eb74343770d8 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-10T14:16:49Z |
| publishDate | 2009-03-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-72c51deafd9a46e2b867eb74343770d82022-12-22T01:45:19Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422009-03-0181391427299Phenotypes of patients with chronic obstructive pulmonary diseaseA V Aver'yanovA G ChuchalinA E PolivanovaG E PolivanovA V ChernyakG V NeklyudovaZh K NaumenkoA V AverianovA G ChuchalinA E PolivanovaG E PolivanovA V ChernyakG V NeklyudovaZh K NaumenkoAim. To study characteristics of phenotypes of chronic obstructive pulmonary disease (COPD) basing on the findings of modern clinical, functional and roentgenomorphological tests in the course of the disease. Material and methods. Basing on the results of high performance computed tomography, 64 COPD patients aged 46-75 years (FEV1 51 ± 24%) were divided into two groups: 53 patients with emphysematous phenotype (group 1) and 11 patients with bronchytic phenotype (group 2). The groups were compared by constitutional, clinical, functional and roentgenological parameters. Results. Group 1 patients had significantly less body mass index, more severe edema by Borg's scale, low FEV1, FEV1/FLC, diffuse lung capacity and lung tissue density compared to group 2. Bronchoectases occurred more frequently in group 1 (33 and 9%, respectively). Conclusion. Heterogenous COPD phenotypes differ not only at the stage of chronic respiratory insufficiency but also at all stages of the disease.https://ter-arkhiv.ru/0040-3660/article/view/30272chronic obstructive pulmonary diseaseemphysematous phenotypebronchytic phenotype |
| spellingShingle | A V Aver'yanov A G Chuchalin A E Polivanova G E Polivanov A V Chernyak G V Neklyudova Zh K Naumenko A V Averianov A G Chuchalin A E Polivanova G E Polivanov A V Chernyak G V Neklyudova Zh K Naumenko Phenotypes of patients with chronic obstructive pulmonary disease Терапевтический архив chronic obstructive pulmonary disease emphysematous phenotype bronchytic phenotype |
| title | Phenotypes of patients with chronic obstructive pulmonary disease |
| title_full | Phenotypes of patients with chronic obstructive pulmonary disease |
| title_fullStr | Phenotypes of patients with chronic obstructive pulmonary disease |
| title_full_unstemmed | Phenotypes of patients with chronic obstructive pulmonary disease |
| title_short | Phenotypes of patients with chronic obstructive pulmonary disease |
| title_sort | phenotypes of patients with chronic obstructive pulmonary disease |
| topic | chronic obstructive pulmonary disease emphysematous phenotype bronchytic phenotype |
| url | https://ter-arkhiv.ru/0040-3660/article/view/30272 |
| work_keys_str_mv | AT avaveryanov phenotypesofpatientswithchronicobstructivepulmonarydisease AT agchuchalin phenotypesofpatientswithchronicobstructivepulmonarydisease AT aepolivanova phenotypesofpatientswithchronicobstructivepulmonarydisease AT gepolivanov phenotypesofpatientswithchronicobstructivepulmonarydisease AT avchernyak phenotypesofpatientswithchronicobstructivepulmonarydisease AT gvneklyudova phenotypesofpatientswithchronicobstructivepulmonarydisease AT zhknaumenko phenotypesofpatientswithchronicobstructivepulmonarydisease AT avaverianov phenotypesofpatientswithchronicobstructivepulmonarydisease AT agchuchalin phenotypesofpatientswithchronicobstructivepulmonarydisease AT aepolivanova phenotypesofpatientswithchronicobstructivepulmonarydisease AT gepolivanov phenotypesofpatientswithchronicobstructivepulmonarydisease AT avchernyak phenotypesofpatientswithchronicobstructivepulmonarydisease AT gvneklyudova phenotypesofpatientswithchronicobstructivepulmonarydisease AT zhknaumenko phenotypesofpatientswithchronicobstructivepulmonarydisease |