Intramolecular CH‐Hydrogen Bonding During the Dissociation of the Oxaphosphetane Intermediate Facilitates Z/E‐Selectivity in Wittig Olefination

Intramolecular CH‐Hydrogen Bonding During the Dissociation of the Oxaphosphetane Intermediate Facilitates Z/E‐Selectivity in Wittig Olefination

Abstract Herein, DFT studies corroborating experimental results revealed that the shortest intramolecular hydrogen bonding distance of cis/trans‐oxaphosphetane (OPA) oxygen with the CH‐hydrogen of a triphenylphosphine phenyl ring provides good evidence for the attained olefin Z/E‐selectivity in Witt...

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Bibliographic Details
Main Authors: Dr. Kukkamudi Sreenivas, Dr. Chintada Nageswara Rao, Dr. Faiz Ahmed Khan
Format: Article
Language:English
Published: Wiley-VCH 2024-03-01
Series:ChemistryOpen
Subjects:
benzylphosphonium salts
Wittig olefination
hydrogen bonding
nitrostilbenes
2-arylindoles
Online Access:https://doi.org/10.1002/open.202300171

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