Cefepime Induced Encephalopathy in a Non-dialysis Dependent Chronic Kidney Disease Patient: A Case Report

Cefepime is a frequently used fourth-generation cephalosporin antibiotic for a wide variety of infections. Toxic levels of this drug can cause neurological complications. The most common neurological adverse event of cefepime is headache and lightheadedness. Here, we presented a case of cefepime ind...

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Main Authors: Giritharan Muniandy, Lydia Kamaruzaman, Tan Hui Jan, Rozita Mohd, Mariamutu Theepa Neesam, Ken Fong Voon, Beng Pau Kiew, Ruslinda Mustafar
Format: Article
Language:English
Published: Interna Publishing 2023-01-01
Series:Acta Medica Indonesiana
Subjects:
Online Access:https://actamedindones.org/index.php/ijim/article/view/1367
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author Giritharan Muniandy
Lydia Kamaruzaman
Tan Hui Jan
Rozita Mohd
Mariamutu Theepa Neesam
Ken Fong Voon
Beng Pau Kiew
Ruslinda Mustafar
author_facet Giritharan Muniandy
Lydia Kamaruzaman
Tan Hui Jan
Rozita Mohd
Mariamutu Theepa Neesam
Ken Fong Voon
Beng Pau Kiew
Ruslinda Mustafar
author_sort Giritharan Muniandy
collection DOAJ
description Cefepime is a frequently used fourth-generation cephalosporin antibiotic for a wide variety of infections. Toxic levels of this drug can cause neurological complications. The most common neurological adverse event of cefepime is headache and lightheadedness. Here, we presented a case of cefepime induced encephalopathy in a 57-year-old female patient with acute on chronic kidney disease. With an accurate diagnosis that requires a high index of clinical suspicion, prompt management was instituted. She had full resolution of symptoms following discontinuation of the medication and also emergent dialysis.
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spelling doaj.art-72c8ab1d167e48508513cbb26313d30b2023-03-31T07:05:07ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322023-01-01551572Cefepime Induced Encephalopathy in a Non-dialysis Dependent Chronic Kidney Disease Patient: A Case ReportGiritharan Muniandy0Lydia Kamaruzaman1Tan Hui Jan2Rozita Mohd3Mariamutu Theepa Neesam4Ken Fong Voon5Beng Pau Kiew6Ruslinda Mustafar7Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, MalaysiaNephrology Unit, Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, MalaysiaNeurology Unit, Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, MalaysiaNephrology Unit, Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, MalaysiaNephrology Unit, Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, MalaysiaNephrology Unit, Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, MalaysiaDepartment of Pharmacy, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, MalaysiaNephrology Unit, Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, MalaysiaCefepime is a frequently used fourth-generation cephalosporin antibiotic for a wide variety of infections. Toxic levels of this drug can cause neurological complications. The most common neurological adverse event of cefepime is headache and lightheadedness. Here, we presented a case of cefepime induced encephalopathy in a 57-year-old female patient with acute on chronic kidney disease. With an accurate diagnosis that requires a high index of clinical suspicion, prompt management was instituted. She had full resolution of symptoms following discontinuation of the medication and also emergent dialysis.https://actamedindones.org/index.php/ijim/article/view/1367cefepimeencephalopathychronic kidney disease
spellingShingle Giritharan Muniandy
Lydia Kamaruzaman
Tan Hui Jan
Rozita Mohd
Mariamutu Theepa Neesam
Ken Fong Voon
Beng Pau Kiew
Ruslinda Mustafar
Cefepime Induced Encephalopathy in a Non-dialysis Dependent Chronic Kidney Disease Patient: A Case Report
Acta Medica Indonesiana
cefepime
encephalopathy
chronic kidney disease
title Cefepime Induced Encephalopathy in a Non-dialysis Dependent Chronic Kidney Disease Patient: A Case Report
title_full Cefepime Induced Encephalopathy in a Non-dialysis Dependent Chronic Kidney Disease Patient: A Case Report
title_fullStr Cefepime Induced Encephalopathy in a Non-dialysis Dependent Chronic Kidney Disease Patient: A Case Report
title_full_unstemmed Cefepime Induced Encephalopathy in a Non-dialysis Dependent Chronic Kidney Disease Patient: A Case Report
title_short Cefepime Induced Encephalopathy in a Non-dialysis Dependent Chronic Kidney Disease Patient: A Case Report
title_sort cefepime induced encephalopathy in a non dialysis dependent chronic kidney disease patient a case report
topic cefepime
encephalopathy
chronic kidney disease
url https://actamedindones.org/index.php/ijim/article/view/1367
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