Gallbladder polyps – a follow-up study after 11 years
Abstract Background The aim of our study was to investigate the prevalence and natural long-term progression of gallbladder polyps in a random sample of the general population. Methods Four hundred and thirteen subjects (190 women, 223 men; aged 29–75 years) were studied first in 2002 and again elev...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-03-01
|
| Series: | BMC Gastroenterology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12876-019-0959-3 |
| _version_ | 1818239999517130752 |
|---|---|
| author | Linda Heitz Wolfgang Kratzer Tilmann Gräter Julian Schmidberger for the EMIL study group |
| author_facet | Linda Heitz Wolfgang Kratzer Tilmann Gräter Julian Schmidberger for the EMIL study group |
| author_sort | Linda Heitz |
| collection | DOAJ |
| description | Abstract Background The aim of our study was to investigate the prevalence and natural long-term progression of gallbladder polyps in a random sample of the general population. Methods Four hundred and thirteen subjects (190 women, 223 men; aged 29–75 years) were studied first in 2002 and again eleven years later in 2013. All subjects were interviewed using a standardised questionnaire, anthropometric data were recorded, and an abdominal ultrasound scan was carried out. Results The prevalence of gallbladder polyps was 6.1% (115/1880) in the 2002 study and 12.1% (50/413) in the 2013 follow-up study. After eleven years, 36 subjects (8.7%, 36/413) had developed new polyps, thirteen subjects (48.1%, 13/27) no longer had gallbladder polyps, and 14 subjects (51.9%, 14/27) still had polyps. The number of polyps had increased in six of these subjects (43%, 6/14), decreased in a further six (43%, 6/14), and remained unchanged in two (14%, 2/14). The mean polyp size was 4.7 mm (± 2.2 mm, range 2–20 mm) in 2002 and 4.0 mm (± 1.9 mm, range 0.5–11 mm) at follow-up. A decrease in polyp size was noted in seven (50%) of the 14 subjects, an increase in size in five subjects (35.7%), and no change in two subjects (14.3%). The shape of the polyps had changed from pedunculated to sessile in two subjects (14.3%, 2/14) and from sessile to pedunculated in one subject (7.1%, 1/14). Conclusions In long-term follow-up, the prevalence of gallbladder polyps increased, with new lesions developing in 8.7% of the population. Polyps persisted in 51.9% of the subjects who had them in the original study and disappeared in the other 48.1%. |
| first_indexed | 2024-12-12T13:06:28Z |
| format | Article |
| id | doaj.art-72cee57c0a69483d93583265aaf23388 |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-12-12T13:06:28Z |
| publishDate | 2019-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-72cee57c0a69483d93583265aaf233882022-12-22T00:23:38ZengBMCBMC Gastroenterology1471-230X2019-03-011911710.1186/s12876-019-0959-3Gallbladder polyps – a follow-up study after 11 yearsLinda Heitz0Wolfgang Kratzer1Tilmann Gräter2Julian Schmidberger3for the EMIL study groupCentre for Internal Medicine, Department of Internal Medicine I, Ulm University HospitalCentre for Internal Medicine, Department of Internal Medicine I, Ulm University HospitalDepartment of Diagnostic and Interventional RadiologyCentre for Internal Medicine, Department of Internal Medicine I, Ulm University HospitalAbstract Background The aim of our study was to investigate the prevalence and natural long-term progression of gallbladder polyps in a random sample of the general population. Methods Four hundred and thirteen subjects (190 women, 223 men; aged 29–75 years) were studied first in 2002 and again eleven years later in 2013. All subjects were interviewed using a standardised questionnaire, anthropometric data were recorded, and an abdominal ultrasound scan was carried out. Results The prevalence of gallbladder polyps was 6.1% (115/1880) in the 2002 study and 12.1% (50/413) in the 2013 follow-up study. After eleven years, 36 subjects (8.7%, 36/413) had developed new polyps, thirteen subjects (48.1%, 13/27) no longer had gallbladder polyps, and 14 subjects (51.9%, 14/27) still had polyps. The number of polyps had increased in six of these subjects (43%, 6/14), decreased in a further six (43%, 6/14), and remained unchanged in two (14%, 2/14). The mean polyp size was 4.7 mm (± 2.2 mm, range 2–20 mm) in 2002 and 4.0 mm (± 1.9 mm, range 0.5–11 mm) at follow-up. A decrease in polyp size was noted in seven (50%) of the 14 subjects, an increase in size in five subjects (35.7%), and no change in two subjects (14.3%). The shape of the polyps had changed from pedunculated to sessile in two subjects (14.3%, 2/14) and from sessile to pedunculated in one subject (7.1%, 1/14). Conclusions In long-term follow-up, the prevalence of gallbladder polyps increased, with new lesions developing in 8.7% of the population. Polyps persisted in 51.9% of the subjects who had them in the original study and disappeared in the other 48.1%.http://link.springer.com/article/10.1186/s12876-019-0959-3Gallbladder polypsPrevalenceLong-term progressionUltrasonography |
| spellingShingle | Linda Heitz Wolfgang Kratzer Tilmann Gräter Julian Schmidberger for the EMIL study group Gallbladder polyps – a follow-up study after 11 years BMC Gastroenterology Gallbladder polyps Prevalence Long-term progression Ultrasonography |
| title | Gallbladder polyps – a follow-up study after 11 years |
| title_full | Gallbladder polyps – a follow-up study after 11 years |
| title_fullStr | Gallbladder polyps – a follow-up study after 11 years |
| title_full_unstemmed | Gallbladder polyps – a follow-up study after 11 years |
| title_short | Gallbladder polyps – a follow-up study after 11 years |
| title_sort | gallbladder polyps a follow up study after 11 years |
| topic | Gallbladder polyps Prevalence Long-term progression Ultrasonography |
| url | http://link.springer.com/article/10.1186/s12876-019-0959-3 |
| work_keys_str_mv | AT lindaheitz gallbladderpolypsafollowupstudyafter11years AT wolfgangkratzer gallbladderpolypsafollowupstudyafter11years AT tilmanngrater gallbladderpolypsafollowupstudyafter11years AT julianschmidberger gallbladderpolypsafollowupstudyafter11years AT fortheemilstudygroup gallbladderpolypsafollowupstudyafter11years |