A Bayesian model selection approach to mediation analysis.

Genetic studies often seek to establish a causal chain of events originating from genetic variation through to molecular and clinical phenotypes. When multiple phenotypes share a common genetic association, one phenotype may act as an intermediate for the genetic effects on the other. Alternatively,...

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Bibliographic Details
Main Authors: Wesley L Crouse, Gregory R Keele, Madeleine S Gastonguay, Gary A Churchill, William Valdar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010184

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