A Bayesian model selection approach to mediation analysis.
Genetic studies often seek to establish a causal chain of events originating from genetic variation through to molecular and clinical phenotypes. When multiple phenotypes share a common genetic association, one phenotype may act as an intermediate for the genetic effects on the other. Alternatively,...
Main Authors: | Wesley L Crouse, Gregory R Keele, Madeleine S Gastonguay, Gary A Churchill, William Valdar |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-05-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1010184 |
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