Identification of Novel Signal Transduction, Immune Function, and Oxidative Stress Genes and Pathways by Topiramate for Treatment of Methamphetamine Dependence Based on Secondary Outcomes

Identification of Novel Signal Transduction, Immune Function, and Oxidative Stress Genes and Pathways by Topiramate for Treatment of Methamphetamine Dependence Based on Secondary Outcomes

BackgroundTopiramate (TPM) is suggested to be a promising medication for treatment of methamphetamine (METH) dependence, but the molecular basis remains to be elucidated.MethodsAmong 140 METH-dependent participants randomly assigned to receive either TPM (N = 69) or placebo (N = 71) in a previously...

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Bibliographic Details
Main Authors: Tianhua Niu, Jingjing Li, Ju Wang, Jennie Z. Ma, Ming D. Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Psychiatry
Subjects:
topiramate
methamphetamine dependence
gene expression profiling
clinical trial
microarray analysis
Online Access:http://journal.frontiersin.org/article/10.3389/fpsyt.2017.00271/full

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