Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of Literature

Hyperleukocytosis is defined as total leukocyte count of more than 100×109 /L. Commonly seen in leukaemic conditions, nonleukaemic causes are usually not encountered and thought of. We report two such non-malignant cases of hyperleukocytosis. A six-year old girl presented with fever, cough and respi...

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Main Authors: Ashutosh Rath, Richa Gupta
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2020-01-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/13409/40556_F(SL)_CE[Ra1]_KM_PF1(AG_KM)_PN(SL).pdf
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author Ashutosh Rath
Richa Gupta
author_facet Ashutosh Rath
Richa Gupta
author_sort Ashutosh Rath
collection DOAJ
description Hyperleukocytosis is defined as total leukocyte count of more than 100×109 /L. Commonly seen in leukaemic conditions, nonleukaemic causes are usually not encountered and thought of. We report two such non-malignant cases of hyperleukocytosis. A six-year old girl presented with fever, cough and respiratory distress with a leukocyte count of 125.97×109 /L. Another case is of a two-month old female infant, who presented with fever and respiratory distress and a leukocyte count of 112.27×109 /L. The present case thrives to highlight various possible causes of hyperleukocytosis with an emphasis on non-malignant causes. Also, important complications and management of hyperleukocytosis are discussed.
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spelling doaj.art-72d9bc48ef6144a3acf57e68adb361012022-12-22T00:13:07ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-01-01141ED01ED0310.7860/JCDR/2020/40556.13409Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of LiteratureAshutosh Rath0Richa Gupta1Senior Resident, Department of Pathology, Maulana Azad Medical College, Delhi, India.Professor, Department of Pathology, Maulana Azad Medical College, Delhi, India.Hyperleukocytosis is defined as total leukocyte count of more than 100×109 /L. Commonly seen in leukaemic conditions, nonleukaemic causes are usually not encountered and thought of. We report two such non-malignant cases of hyperleukocytosis. A six-year old girl presented with fever, cough and respiratory distress with a leukocyte count of 125.97×109 /L. Another case is of a two-month old female infant, who presented with fever and respiratory distress and a leukocyte count of 112.27×109 /L. The present case thrives to highlight various possible causes of hyperleukocytosis with an emphasis on non-malignant causes. Also, important complications and management of hyperleukocytosis are discussed.https://jcdr.net/articles/PDF/13409/40556_F(SL)_CE[Ra1]_KM_PF1(AG_KM)_PN(SL).pdfbenignleukocytosisleukostasis
spellingShingle Ashutosh Rath
Richa Gupta
Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of Literature
Journal of Clinical and Diagnostic Research
benign
leukocytosis
leukostasis
title Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of Literature
title_full Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of Literature
title_fullStr Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of Literature
title_full_unstemmed Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of Literature
title_short Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of Literature
title_sort hyperleukocytosis re visited is it always leukaemia a report of two cases and review of literature
topic benign
leukocytosis
leukostasis
url https://jcdr.net/articles/PDF/13409/40556_F(SL)_CE[Ra1]_KM_PF1(AG_KM)_PN(SL).pdf
work_keys_str_mv AT ashutoshrath hyperleukocytosisrevisitedisitalwaysleukaemiaareportoftwocasesandreviewofliterature
AT richagupta hyperleukocytosisrevisitedisitalwaysleukaemiaareportoftwocasesandreviewofliterature