Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data

Abstract As society continues to age, it is becoming increasingly important to monitor drug use in the elderly. Social media data have been used for monitoring adverse drug reactions. The aim of this study was to determine whether social network studies (SNS) are useful sources of drug side effects...

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Main Authors: Seunghee Lee, Hyekyung Woo, Chung Chun Lee, Gyeongmin Kim, Jong-Yeup Kim, Suehyun Lee
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28912-6
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author Seunghee Lee
Hyekyung Woo
Chung Chun Lee
Gyeongmin Kim
Jong-Yeup Kim
Suehyun Lee
author_facet Seunghee Lee
Hyekyung Woo
Chung Chun Lee
Gyeongmin Kim
Jong-Yeup Kim
Suehyun Lee
author_sort Seunghee Lee
collection DOAJ
description Abstract As society continues to age, it is becoming increasingly important to monitor drug use in the elderly. Social media data have been used for monitoring adverse drug reactions. The aim of this study was to determine whether social network studies (SNS) are useful sources of drug side effects information. We propose a method for utilizing SNS data to plot the known side effects of geriatric drugs in a dosing map. We developed a lexicon of drug terms associated with side effects and mapped patterns from social media data. We confirmed that well-known side effects may be obtained by utilizing SNS data. Based on these results, we propose a pharmacovigilance pipeline that can be extended to unknown side effects. We propose the standard analysis pipeline Drug_SNSMiner for monitoring side effects using SNS data and evaluated it as a drug prescription platform for the elderly. We confirmed that side effects may be monitored from the consumer’s perspective based on SNS data using only drug information. SNS data were deemed good sources of information to determine ADRs and obtain other complementary data. We established that these learning data are invaluable for AI requiring the acquisition of ADR posts on efficacious drugs.
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spelling doaj.art-72df96ed7cf84811b866cd362f1979152023-03-22T11:12:55ZengNature PortfolioScientific Reports2045-23222023-03-0113111010.1038/s41598-023-28912-6Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS dataSeunghee Lee0Hyekyung Woo1Chung Chun Lee2Gyeongmin Kim3Jong-Yeup Kim4Suehyun Lee5Healthcare Data Science Center, Konyang University HospitalDepartment of Health Administration, Kongju National UniversityDepartment of Biomedical Informatics, College of Medicine, Konyang UniversityDepartment of Biomedical Engineering, Konyang UniversityHealthcare Data Science Center, Konyang University HospitalCollege of IT Convergence, Gachon UniversityAbstract As society continues to age, it is becoming increasingly important to monitor drug use in the elderly. Social media data have been used for monitoring adverse drug reactions. The aim of this study was to determine whether social network studies (SNS) are useful sources of drug side effects information. We propose a method for utilizing SNS data to plot the known side effects of geriatric drugs in a dosing map. We developed a lexicon of drug terms associated with side effects and mapped patterns from social media data. We confirmed that well-known side effects may be obtained by utilizing SNS data. Based on these results, we propose a pharmacovigilance pipeline that can be extended to unknown side effects. We propose the standard analysis pipeline Drug_SNSMiner for monitoring side effects using SNS data and evaluated it as a drug prescription platform for the elderly. We confirmed that side effects may be monitored from the consumer’s perspective based on SNS data using only drug information. SNS data were deemed good sources of information to determine ADRs and obtain other complementary data. We established that these learning data are invaluable for AI requiring the acquisition of ADR posts on efficacious drugs.https://doi.org/10.1038/s41598-023-28912-6
spellingShingle Seunghee Lee
Hyekyung Woo
Chung Chun Lee
Gyeongmin Kim
Jong-Yeup Kim
Suehyun Lee
Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
Scientific Reports
title Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_full Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_fullStr Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_full_unstemmed Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_short Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS data
title_sort drug snsminer standard pharmacovigilance pipeline for detection of adverse drug reaction using sns data
url https://doi.org/10.1038/s41598-023-28912-6
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