Structural and functional analysis of the roles of the HCV 5′ NCR miR122-dependent long-range association and SLVI in genome translation and replication

Structural and functional analysis of the roles of the HCV 5′ NCR miR122-dependent long-range association and SLVI in genome translation and replication

The hepatitis C virus RNA genome possesses a variety of conserved structural elements, in both coding and non-coding regions, that are important for viral replication. These elements are known or predicted to modulate key life cycle events, such as translation and genome replication, some involving...

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Bibliographic Details
Main Authors: Kirsten Bentley, Jonathan P. Cook, Andrew K. Tuplin, David J. Evans
Format: Article
Language:English
Published: PeerJ Inc. 2018-11-01
Series:PeerJ
Subjects:
Hepatitis C virus
RNA–RNA interaction
SHAPE
miR122
Riboswitch
Online Access:https://peerj.com/articles/5870.pdf

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