Neuregulin 1 expression and electrophysiological abnormalities in the Neuregulin 1 transmembrane domain heterozygous mutant mouse.

Neuregulin 1 expression and electrophysiological abnormalities in the Neuregulin 1 transmembrane domain heterozygous mutant mouse.

The Neuregulin 1 transmembrane domain heterozygous mutant (Nrg1 TM HET) mouse is used to investigate the role of Nrg1 in brain function and schizophrenia-like behavioural phenotypes. However, the molecular alterations in brain Nrg1 expression that underpin the behavioural observations have been assu...

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Bibliographic Details
Main Authors: Leonora E Long, Paul Anderson, Elisabeth Frank, Alex Shaw, Shijie Liu, Xu-Feng Huang, Didier Pinault, Tim Karl, Terence J O'Brien, Cynthia Shannon Weickert, Nigel C Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4437646?pdf=render

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