Does surgery affect systemic immune response? a perioperative analysis of TGF-β, IL-8 and CD45RO

Does surgery affect systemic immune response? a perioperative analysis of TGF-β, IL-8 and CD45RO

BackgroundThe options of (neo-)adjuvant immunotherapy in addition to surgery in the treatment of oral squamous cell carcinoma (OSCC) are steadily increasing, but patients do not always respond to therapy as intended. The objectives of this study were to investigate the systemic perioperative course...

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Bibliographic Details
Main Authors: Leah Trumet, Jutta Ries, Niclas Ivenz, Philip Sobl, Falk Wehrhan, Rainer Lutz, Marco Kesting, Manuel Weber
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Oncology
Subjects:
perioperative systemic changes of signaling pathways immune tolerance
OSCC
HNSCC
surgery
interleukins
oral surgery
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1307956/full

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