Enhancing CAR T-cell therapies against solid tumors: Mechanisms and reversion of resistance

Enhancing CAR T-cell therapies against solid tumors: Mechanisms and reversion of resistance

Chimeric antigen receptor (CAR) T-cell therapy, belonging to adoptive immune cells therapy, utilizes engineered immunoreceptors to enhance tumor-specific killing. By now new generations of CAR T-cell therapies dramatically promote the effectiveness and robustness in leukemia cases. However, only a f...

Full description

Bibliographic Details
Main Authors: Yue Qin, Guotai Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
CAR T-cell
solid tumor
antigen viability
microenvironment
tumor infitration
combined therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1053120/full

Similar Items

Similar Items