Optic nerve head plasmacytoma as a manifestation of multiple myeloma

Extramedullary disease in multiple myeloma is uncommon and associated with a poorer prognosis. Extramedullary disease involving the orbit is even more unusual, with optic nerve involvement being rare. We describe an optic nerve head plasmacytoma in a 45-year-old female in the setting of systemic rel...

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Bibliographic Details
Main Authors: Kaitlin P Sandor, Jonathan A Micieli, Jason H Peragallo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Taiwan Journal of Ophthalmology
Subjects:
Online Access:http://www.e-tjo.org/article.asp?issn=2211-5056;year=2021;volume=11;issue=1;spage=97;epage=100;aulast=Sandor
Description
Summary:Extramedullary disease in multiple myeloma is uncommon and associated with a poorer prognosis. Extramedullary disease involving the orbit is even more unusual, with optic nerve involvement being rare. We describe an optic nerve head plasmacytoma in a 45-year-old female in the setting of systemic relapsed, refractory IgA kappa multiple myeloma. The case highlights the importance of keeping extramedullary disease spread in the differential for vision loss in a patient with a history of multiple myeloma. In addition, it describes an unusual location for presentation of extramedullary disease, the optic nerve head, which has rarely been described.
ISSN:2211-5056
2211-5072