Bacterial Type I Toxins: Folding and Membrane Interactions

Bacterial Type I Toxins: Folding and Membrane Interactions

Bacterial type I toxin-antitoxin systems are two-component genetic modules that encode a stable toxic protein whose ectopic overexpression can lead to growth arrest or cell death, and an unstable RNA antitoxin that inhibits toxin translation during growth. These systems are widely spread among bacte...

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Bibliographic Details
Main Authors: Sylvie Nonin-Lecomte, Laurence Fermon, Brice Felden, Marie-Laure Pinel-Marie
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Toxins
Subjects:
toxin-antitoxin systems
type I toxins
mechanisms of action
membrane depolarization
membrane permeabilization
pore formation
Online Access:https://www.mdpi.com/2072-6651/13/7/490

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