Cell origin and genome profile difference of penoscrotum invasive extramammary Paget disease compared with its in situ counterpart

Cell origin and genome profile difference of penoscrotum invasive extramammary Paget disease compared with its in situ counterpart

Penoscrotum extramammary Paget disease (pEMPD) is a rare cutaneous carcinoma with an unknown cell origin. pEMPD always presents as a tumor in situ with an indolent process, whereas some progress into invasive forms with more aggressive behavior. The in situ and invasive cases display different morph...

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Bibliographic Details
Main Authors: Yamin Rao, Jinchao Zhu, Haiyan Zheng, Yong Ren, Tianhai Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
cell origin
genome profiles
extramammary Paget disease (EMPD)
invasive
in situ
penoscrotum
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.972047/full

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