Allosteric communication occurs via networks of tertiary and quaternary motions in proteins.
Allosteric proteins bind an effector molecule at one site resulting in a functional change at a second site. We hypothesize that allosteric communication in proteins relies upon networks of quaternary (collective, rigid-body) and tertiary (residue-residue contact) motions. We argue that cyclic topol...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-02-01
|
| Series: | PLoS Computational Biology |
| Online Access: | http://europepmc.org/articles/PMC2634971?pdf=render |