Effect of caffeine-loaded silver nanoparticles on minerals concentration and antibacterial activity in rats
Background: Caffeine boosts metabolism and the neurological system. When extreme weakness or sleepiness occurs, it is used recreationally and medicinally to reduce physical and mental fatigue. Caffeine initially stimulates the central nervous system, increasing intellect, speed, accuracy, focus, and...
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| Format: | Article |
| Language: | English |
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Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology
2023-08-01
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| Series: | Journal of Advanced Biotechnology and Experimental Therapeutics |
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| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=145496 |
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| author | Mohammed Rasheed Maysoon M N M Saleem Thorria R. Marzoog Malaa M. Taki Dikra Bouras Israa A. Hashim Mustafa Nuhad Al-Darraji Raad Rasheed Mohammed Abdulhadi Sarhan |
| author_facet | Mohammed Rasheed Maysoon M N M Saleem Thorria R. Marzoog Malaa M. Taki Dikra Bouras Israa A. Hashim Mustafa Nuhad Al-Darraji Raad Rasheed Mohammed Abdulhadi Sarhan |
| author_sort | Mohammed Rasheed |
| collection | DOAJ |
| description | Background: Caffeine boosts metabolism and the neurological system. When extreme weakness or sleepiness occurs, it is used recreationally and medicinally to reduce physical and mental fatigue. Caffeine initially stimulates the central nervous system, increasing intellect, speed, accuracy, focus, and coordination. Objective: To evaluate how caffeine nanoparticles affect potassium, calcium, zinc, and magnesium levels, in addition, the anti-bacterial activity of the samples has been employed. Methods: Eighteen male albino rats were divided into three separate groups. The first group (G1) was made up of six animals that served as a control group. The second group (G2) was made up of six animals that were given caffeine, and the third group (G3) was made up of six animals that were given silver nanoparticles from a caffeine solution. The particle size and structural morphology of Caffeine and silver nanoparticles were analyzed using Brookhaven Instruments Corp., XRD and SEM respectively. Results: The structural results showed after addition, caffeine was tube-shaped and silver was spherical granular. Caffeine has more silver nanoparticles than caffeine solution. Caffeine solution affects potassium, calcium, zinc, and magnesium levels. Additionally, the solution has antibacterial activity against the following bacteria: Staphylococcus aureus (Gram +ve), E. coli (Gram –ve), and Pseudomonas aeruginosa (Gram-ve), but it has no effect against yeast (Candida albicans). Conclusions: To determine the biological effects of caffeine-synthesized Ag NPs on zinc, magnesium, calcium, and potassium levels in male albino mice's serum, this is antibacterial against staphylococcus. [ J Adv Biotechnol Exp Ther 2023; 6(2.000): 495-509] |
| first_indexed | 2024-03-13T08:39:09Z |
| format | Article |
| id | doaj.art-72f7d41a051f482d9fe49549890f2074 |
| institution | Directory Open Access Journal |
| issn | 2616-4760 |
| language | English |
| last_indexed | 2024-03-13T08:39:09Z |
| publishDate | 2023-08-01 |
| publisher | Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology |
| record_format | Article |
| series | Journal of Advanced Biotechnology and Experimental Therapeutics |
| spelling | doaj.art-72f7d41a051f482d9fe49549890f20742023-05-30T15:42:12ZengBangladesh Society for Microbiology, Immunology, and Advanced BiotechnologyJournal of Advanced Biotechnology and Experimental Therapeutics2616-47602023-08-0162495509145496Effect of caffeine-loaded silver nanoparticles on minerals concentration and antibacterial activity in ratsMohammed Rasheed0Maysoon M N M Saleem1Thorria R. Marzoog2Malaa M. Taki3Dikra Bouras4Israa A. Hashim5Mustafa Nuhad Al-Darraji6Raad Rasheed7Mohammed Abdulhadi SarhanDepartment of Applied Sciences, University of Technology, Baghdad, Iraq. Applied Sciences Department, University of Technology, Baghdad, Iraq. Applied Sciences Department, University of Technology, Baghdad, Iraq. Nanotechnology and Advanced Research Center, University of Technology-Iraq, Baghdad, Iraq Laboratory of Active Components and Materials, Larbi Ben M'Hidi University, Oum El Bouaghi 04000, Algeria Nanotechnology and Advanced Research Center, University of Technology-Iraq, Baghdad, Iraq Department of Biology, College of Science, University Of Al-Anbar, Anbar, Iraq Al-Shirqat General Hospital, Salah Al-Deen Directorate of Health Government, Ministry of Health, IraqBackground: Caffeine boosts metabolism and the neurological system. When extreme weakness or sleepiness occurs, it is used recreationally and medicinally to reduce physical and mental fatigue. Caffeine initially stimulates the central nervous system, increasing intellect, speed, accuracy, focus, and coordination. Objective: To evaluate how caffeine nanoparticles affect potassium, calcium, zinc, and magnesium levels, in addition, the anti-bacterial activity of the samples has been employed. Methods: Eighteen male albino rats were divided into three separate groups. The first group (G1) was made up of six animals that served as a control group. The second group (G2) was made up of six animals that were given caffeine, and the third group (G3) was made up of six animals that were given silver nanoparticles from a caffeine solution. The particle size and structural morphology of Caffeine and silver nanoparticles were analyzed using Brookhaven Instruments Corp., XRD and SEM respectively. Results: The structural results showed after addition, caffeine was tube-shaped and silver was spherical granular. Caffeine has more silver nanoparticles than caffeine solution. Caffeine solution affects potassium, calcium, zinc, and magnesium levels. Additionally, the solution has antibacterial activity against the following bacteria: Staphylococcus aureus (Gram +ve), E. coli (Gram –ve), and Pseudomonas aeruginosa (Gram-ve), but it has no effect against yeast (Candida albicans). Conclusions: To determine the biological effects of caffeine-synthesized Ag NPs on zinc, magnesium, calcium, and potassium levels in male albino mice's serum, this is antibacterial against staphylococcus. [ J Adv Biotechnol Exp Ther 2023; 6(2.000): 495-509]http://www.ejmanager.com/fulltextpdf.php?mno=145496caffeine; ag (npls); antibacterial activity; metal concentrationnanotechnology |
| spellingShingle | Mohammed Rasheed Maysoon M N M Saleem Thorria R. Marzoog Malaa M. Taki Dikra Bouras Israa A. Hashim Mustafa Nuhad Al-Darraji Raad Rasheed Mohammed Abdulhadi Sarhan Effect of caffeine-loaded silver nanoparticles on minerals concentration and antibacterial activity in rats Journal of Advanced Biotechnology and Experimental Therapeutics caffeine; ag (npls); antibacterial activity; metal concentration nanotechnology |
| title | Effect of caffeine-loaded silver nanoparticles on minerals concentration and antibacterial activity in rats |
| title_full | Effect of caffeine-loaded silver nanoparticles on minerals concentration and antibacterial activity in rats |
| title_fullStr | Effect of caffeine-loaded silver nanoparticles on minerals concentration and antibacterial activity in rats |
| title_full_unstemmed | Effect of caffeine-loaded silver nanoparticles on minerals concentration and antibacterial activity in rats |
| title_short | Effect of caffeine-loaded silver nanoparticles on minerals concentration and antibacterial activity in rats |
| title_sort | effect of caffeine loaded silver nanoparticles on minerals concentration and antibacterial activity in rats |
| topic | caffeine; ag (npls); antibacterial activity; metal concentration nanotechnology |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=145496 |
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