Determination of Lead in Human Calculi and Its Effects on Renal Function of Lead Occupational Workers

Seventy five samples of renal and eighteen samples of supra gingival calculi of lead recycling workers were collected over the period of seven years (2008-2014) and studied for the accumulation of lead. The results were compared with those of non exposed subjects. The lead content of calculi was inv...

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Main Authors: F. Memon, N.T. Narejo, A. G. M. Vasandani, K. P. Kunbhar, S. Jalbani, P. Khan
Format: Article
Language:English
Published: National Centre of Excellence in Analytical Chemsitry 2016-06-01
Series:Pakistan Journal of Analytical & Environmental Chemistry
Subjects:
Online Access:http://www.ceacsu.edu.pk/PDF%20file/Volume%2017/11.pdf
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author F. Memon
N.T. Narejo
A. G. M. Vasandani
K. P. Kunbhar
S. Jalbani
P. Khan
author_facet F. Memon
N.T. Narejo
A. G. M. Vasandani
K. P. Kunbhar
S. Jalbani
P. Khan
author_sort F. Memon
collection DOAJ
description Seventy five samples of renal and eighteen samples of supra gingival calculi of lead recycling workers were collected over the period of seven years (2008-2014) and studied for the accumulation of lead. The results were compared with those of non exposed subjects. The lead content of calculi was investigated for its dependence on type and composition of calculi, blood lead, job status and duration of exposure. The effect of blood lead and renal calculi was also investigated in relation to kidney function of respective subjects. The mean lead levels of various types of calculi were found to follow the order as phosphate > oxalate > urate .> cystine while single principal group of supra gingival calculi resulted in lower levels of metal. The lead content of calculi positively correlated with phosphate content of both of the renal (r = 0.655) and supra gingival calculi (r= 0.866), Impaired renal function was more pronounced in active workers and depended on blood lead levels in addition to presence of metal in renal calculi
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spelling doaj.art-72f85ba9c9b44157b0068de2f22815b12022-12-22T01:35:51ZengNational Centre of Excellence in Analytical ChemsitryPakistan Journal of Analytical & Environmental Chemistry1996-918X2221-52552016-06-01171727610.21743/pjaec/2016.06.011Determination of Lead in Human Calculi and Its Effects on Renal Function of Lead Occupational WorkersF. MemonN.T. NarejoA. G. M. Vasandani K. P. KunbharS. JalbaniP. KhanSeventy five samples of renal and eighteen samples of supra gingival calculi of lead recycling workers were collected over the period of seven years (2008-2014) and studied for the accumulation of lead. The results were compared with those of non exposed subjects. The lead content of calculi was investigated for its dependence on type and composition of calculi, blood lead, job status and duration of exposure. The effect of blood lead and renal calculi was also investigated in relation to kidney function of respective subjects. The mean lead levels of various types of calculi were found to follow the order as phosphate > oxalate > urate .> cystine while single principal group of supra gingival calculi resulted in lower levels of metal. The lead content of calculi positively correlated with phosphate content of both of the renal (r = 0.655) and supra gingival calculi (r= 0.866), Impaired renal function was more pronounced in active workers and depended on blood lead levels in addition to presence of metal in renal calculihttp://www.ceacsu.edu.pk/PDF%20file/Volume%2017/11.pdfLithiasisLead poisoningCreatinineBattery recyclingLead nephropathy
spellingShingle F. Memon
N.T. Narejo
A. G. M. Vasandani
K. P. Kunbhar
S. Jalbani
P. Khan
Determination of Lead in Human Calculi and Its Effects on Renal Function of Lead Occupational Workers
Pakistan Journal of Analytical & Environmental Chemistry
Lithiasis
Lead poisoning
Creatinine
Battery recycling
Lead nephropathy
title Determination of Lead in Human Calculi and Its Effects on Renal Function of Lead Occupational Workers
title_full Determination of Lead in Human Calculi and Its Effects on Renal Function of Lead Occupational Workers
title_fullStr Determination of Lead in Human Calculi and Its Effects on Renal Function of Lead Occupational Workers
title_full_unstemmed Determination of Lead in Human Calculi and Its Effects on Renal Function of Lead Occupational Workers
title_short Determination of Lead in Human Calculi and Its Effects on Renal Function of Lead Occupational Workers
title_sort determination of lead in human calculi and its effects on renal function of lead occupational workers
topic Lithiasis
Lead poisoning
Creatinine
Battery recycling
Lead nephropathy
url http://www.ceacsu.edu.pk/PDF%20file/Volume%2017/11.pdf
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