Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R

Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R

<p>Abstract</p> <p>Background</p> <p>Cell cycle G2 arrest induced by HIV-1 Vpr is thought to benefit viral proliferation by providing an optimized cellular environment for viral replication and by skipping host immune responses. Even though Vpr-induced G2 arrest has bee...

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Bibliographic Details
Main Authors: Liang Dong, Park Hyeon U, Li Ge, Zhao Richard Y
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/7/1/59

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