Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study
Summary: Background: Differences in survival between groups may reflect avoidable and modifiable inequalities. This study examines the 35-year mortality risk for adults aged 25–44 years in the mid-1980s with disability due to vision, hearing, or motor impairment; physical illness; or mental health...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-11-01
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| Series: | The Lancet Regional Health. Europe |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666776222001788 |
| _version_ | 1798041993282060288 |
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| author | Ellen Melbye Langballe Gro Gujord Tangen Bo Engdahl Bjørn Heine Strand |
| author_facet | Ellen Melbye Langballe Gro Gujord Tangen Bo Engdahl Bjørn Heine Strand |
| author_sort | Ellen Melbye Langballe |
| collection | DOAJ |
| description | Summary: Background: Differences in survival between groups may reflect avoidable and modifiable inequalities. This study examines the 35-year mortality risk for adults aged 25–44 years in the mid-1980s with disability due to vision, hearing, or motor impairment; physical illness; or mental health problems. Methods: This Norwegian study was based on data from the Trøndelag Health Study (HUNT1, 1984–86, and HUNT2, 1995–97) linked to tax-registry data for deaths before 15 November 2019. Mortality risk was estimated by Cox regression analysis adjusted for age and sex. Sensitivity analysis included the following possible mediators: education, work, living situation, body mass index, systolic blood pressure and smoking. Findings: Of the 30,080 HUNT1 participants aged 25–44 years, 5071 (16.9%) reported having disability. During the 35 years of follow-up, 1069 (21.1%) participants with disability and 3107 (12.4%) without disability died. Individuals with any type of disability had 62% higher mortality risk compared to those without a disability, adjusted by age and sex. The highest mortality risks were observed for disability due to severe motor impairment (HR=3.67, 95%CI=2.89–4.67) and severe mental health problems (HR=3.40, 95%CI=2.75–4.23) compared to those without these disabilities. Increased mortality risk was found for all the included disability types. The associations were somewhat mediated, especially by education, work and living situation. Interpretation: This study shows that among adults aged 25–44 years, the risk of death increases with disability of different types and severity levels, particularly for disability related to mental health problems or motor impairment. Funding: None. |
| first_indexed | 2024-04-11T22:29:18Z |
| format | Article |
| id | doaj.art-72fa3f3453db40189cb38182b6e9cf5d |
| institution | Directory Open Access Journal |
| issn | 2666-7762 |
| language | English |
| last_indexed | 2024-04-11T22:29:18Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | The Lancet Regional Health. Europe |
| spelling | doaj.art-72fa3f3453db40189cb38182b6e9cf5d2022-12-22T03:59:33ZengElsevierThe Lancet Regional Health. Europe2666-77622022-11-0122100482Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT studyEllen Melbye Langballe0Gro Gujord Tangen1Bo Engdahl2Bjørn Heine Strand3Norwegian National Centre for Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway; Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway; Corresponding author.Norwegian National Centre for Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway; Department of Geriatric Medicine, Oslo University Hospital, Oslo, NorwayDepartment for Physical Health and Ageing, Norwegian Institute of Public Health, Oslo, NorwayNorwegian National Centre for Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway; Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway; Department for Physical Health and Ageing, Norwegian Institute of Public Health, Oslo, NorwaySummary: Background: Differences in survival between groups may reflect avoidable and modifiable inequalities. This study examines the 35-year mortality risk for adults aged 25–44 years in the mid-1980s with disability due to vision, hearing, or motor impairment; physical illness; or mental health problems. Methods: This Norwegian study was based on data from the Trøndelag Health Study (HUNT1, 1984–86, and HUNT2, 1995–97) linked to tax-registry data for deaths before 15 November 2019. Mortality risk was estimated by Cox regression analysis adjusted for age and sex. Sensitivity analysis included the following possible mediators: education, work, living situation, body mass index, systolic blood pressure and smoking. Findings: Of the 30,080 HUNT1 participants aged 25–44 years, 5071 (16.9%) reported having disability. During the 35 years of follow-up, 1069 (21.1%) participants with disability and 3107 (12.4%) without disability died. Individuals with any type of disability had 62% higher mortality risk compared to those without a disability, adjusted by age and sex. The highest mortality risks were observed for disability due to severe motor impairment (HR=3.67, 95%CI=2.89–4.67) and severe mental health problems (HR=3.40, 95%CI=2.75–4.23) compared to those without these disabilities. Increased mortality risk was found for all the included disability types. The associations were somewhat mediated, especially by education, work and living situation. Interpretation: This study shows that among adults aged 25–44 years, the risk of death increases with disability of different types and severity levels, particularly for disability related to mental health problems or motor impairment. Funding: None.http://www.sciencedirect.com/science/article/pii/S2666776222001788Mortality riskDisabilityVision impairmentHearing impairmentMotor impairmentPhysical illness |
| spellingShingle | Ellen Melbye Langballe Gro Gujord Tangen Bo Engdahl Bjørn Heine Strand Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study The Lancet Regional Health. Europe Mortality risk Disability Vision impairment Hearing impairment Motor impairment Physical illness |
| title | Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study |
| title_full | Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study |
| title_fullStr | Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study |
| title_full_unstemmed | Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study |
| title_short | Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study |
| title_sort | increased mortality risk for adults aged 25 44 years with long term disability a prospective cohort study with a 35 year follow up of 30 080 individuals from 1984 2019 in the population based hunt study |
| topic | Mortality risk Disability Vision impairment Hearing impairment Motor impairment Physical illness |
| url | http://www.sciencedirect.com/science/article/pii/S2666776222001788 |
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