CD147 Facilitates the Pathogenesis of Psoriasis through Glycolysis and H3K9me3 Modification in Keratinocytes
Psoriasis is a chronic inflammatory skin disease featuring rapid proliferation of epidermal cells. Although elevated glycolysis flux has been reported in psoriasis, the molecular mechanisms underlying its pathogenesis remain unclear. We investigated the role of the integral membrane protein CD147 in...
Main Authors: | Chao Chen, Xiaoqing Yi, Panpan Liu, Jie Li, Bei Yan, Detian Zhang, Lei Zhu, Pian Yu, Lei Li, Jiaxiong Zhang, Yehong Kuang, Shuang Zhao, Wu Zhu, Cong Peng, Xiang Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2023-01-01
|
Series: | Research |
Online Access: | https://spj.science.org/doi/10.34133/research.0167 |
Similar Items
-
The CD147 expression in CD4+ T cells is a novel biomarker for predicting efficacy of IL‐17A inhibitor and psoriasis recurrence
by: Panpan Liu, et al.
Published: (2024-02-01) -
Pyruvate Kinase M2 Mediates Glycolysis Contributes to Psoriasis by Promoting Keratinocyte Proliferation
by: Yun-zi Liu, et al.
Published: (2021-10-01) -
Acitretin Promotes the Differentiation of Myeloid-Derived Suppressor Cells in the Treatment of Psoriasis
by: Panpan Liu, et al.
Published: (2021-03-01) -
Predicting the Risk of Psoriatic Arthritis in Plaque Psoriasis Patients: Development and Assessment of a New Predictive Nomogram
by: Panpan Liu, et al.
Published: (2022-01-01) -
Benzoylaconitine Alleviates Progression of Psoriasis via Suppressing STAT3 Phosphorylation in Keratinocytes
by: Yuanbo Li, et al.
Published: (2023-05-01)