Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM
Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2018-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-05441-9 |
| _version_ | 1828976608359219200 |
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| author | S. Rempel E. Colucci J. W. de Gier A. Guskov D. J. Slotboom |
| author_facet | S. Rempel E. Colucci J. W. de Gier A. Guskov D. J. Slotboom |
| author_sort | S. Rempel |
| collection | DOAJ |
| description | Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter. |
| first_indexed | 2024-12-14T14:41:50Z |
| format | Article |
| id | doaj.art-72fc0697a8c449729feb9bbe1e3643d9 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T14:41:50Z |
| publishDate | 2018-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-72fc0697a8c449729feb9bbe1e3643d92022-12-21T22:57:24ZengNature PortfolioNature Communications2041-17232018-08-01911810.1038/s41467-018-05441-9Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuMS. Rempel0E. Colucci1J. W. de Gier2A. Guskov3D. J. Slotboom4Groningen Biomolecular and Biotechnology Institute (GBB), University of GroningenGroningen Biomolecular and Biotechnology Institute (GBB), University of GroningenDepartment of Biochemistry and Biophysics, Stockholm UniversityGroningen Biomolecular and Biotechnology Institute (GBB), University of GroningenGroningen Biomolecular and Biotechnology Institute (GBB), University of GroningenUptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.https://doi.org/10.1038/s41467-018-05441-9 |
| spellingShingle | S. Rempel E. Colucci J. W. de Gier A. Guskov D. J. Slotboom Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM Nature Communications |
| title | Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
| title_full | Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
| title_fullStr | Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
| title_full_unstemmed | Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
| title_short | Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM |
| title_sort | cysteine mediated decyanation of vitamin b12 by the predicted membrane transporter btum |
| url | https://doi.org/10.1038/s41467-018-05441-9 |
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