Methicillin-Resistant Staphylococcus aureus Using Broth Micro Dilution Method in Iran: A Meta-Analysis (2007-2016)
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most signifuicant pathogens in Iran; it is one of the WHO-declared microbial resistance emergencies; and also one of the most important challenges facing the prevalence of resistance. The aim of this study was to detec...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2018-10-01
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| Series: | Journal of Medical Bacteriology |
| Subjects: | |
| Online Access: | https://jmb.tums.ac.ir/index.php/jmb/article/view/329 |
| _version_ | 1828434618133512192 |
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| author | Ghobad Moradi Seyyede Maryam Bechashk Nader Esmailnasab Behzad Mohsenpour Rashid Ramazanzadeh Daem Roshani Ebrahim Ghaderi |
| author_facet | Ghobad Moradi Seyyede Maryam Bechashk Nader Esmailnasab Behzad Mohsenpour Rashid Ramazanzadeh Daem Roshani Ebrahim Ghaderi |
| author_sort | Ghobad Moradi |
| collection | DOAJ |
| description | Background: Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most signifuicant pathogens in Iran; it is one of the WHO-declared microbial resistance emergencies; and also one of the most important challenges facing the prevalence of resistance. The aim of this study was to detect MRSA using Broth Micro Dilution method and meta-analysis in Iran from 2007 to 2016.
Methods: Persian databases (including Magiran, Irandoc, and SID) and International databases (including pubmed, science direct, and scopus) were searched during this period (2007-2016), such that the high heterogeneity (50% < I2) in this study was analyzed using the DerSimonian Laird method. Data were categorized into subgroups based on year of study and province. Due to the high validity of the diagnosis of organisms and quantitative results, antimicrobial susceptibility test (AST) was used to detect MRSA. Data analysis was performed using statsdirect software.
Results: Based on the available data in medical databases, 678 articles were selected. In total, 29 remaining studies entered the meta-analysis phase. In this study, the overall prevalence of MRSA using MIC is 53% (95% CI: 0.42.31, 63.90); in 2016 it was 77.56% (95% CI: 76.07, 78.99) and in 2007 was 57.49% (95% CI: 53.17, 61.72). The heterogeneity was estimated to be 98.5% (95% CI: 98.4, 98.6).
Conclusion: Based on the results, there is an increasing prevalence of MRSA in Iran. These may be due to the failure or lack of infection control activities and antimicrobial selection pressure. |
| first_indexed | 2024-12-10T18:52:35Z |
| format | Article |
| id | doaj.art-72fe8305ad644a1c8dac0434d9ee173a |
| institution | Directory Open Access Journal |
| issn | 2251-8649 2322-2581 |
| language | English |
| last_indexed | 2024-12-10T18:52:35Z |
| publishDate | 2018-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Medical Bacteriology |
| spelling | doaj.art-72fe8305ad644a1c8dac0434d9ee173a2022-12-22T01:37:15ZengTehran University of Medical SciencesJournal of Medical Bacteriology2251-86492322-25812018-10-0173-4329Methicillin-Resistant Staphylococcus aureus Using Broth Micro Dilution Method in Iran: A Meta-Analysis (2007-2016)Ghobad Moradi0Seyyede Maryam Bechashk1Nader Esmailnasab2Behzad Mohsenpour3Rashid Ramazanzadeh4Daem Roshani5Ebrahim Ghaderi6Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.Department of infectious Disease, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, IranCellular and Molecular Research Center and Microbiology Department, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, IranDepartment of Epidemiology and Biostatistics, Medical School, Kurdistan University of Sciences, Sanandaj, Iran.Department of Epidemiology and Biostatistics, Medical School, Kurdistan University of Sciences, Sanandaj, Iran.Background: Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most signifuicant pathogens in Iran; it is one of the WHO-declared microbial resistance emergencies; and also one of the most important challenges facing the prevalence of resistance. The aim of this study was to detect MRSA using Broth Micro Dilution method and meta-analysis in Iran from 2007 to 2016. Methods: Persian databases (including Magiran, Irandoc, and SID) and International databases (including pubmed, science direct, and scopus) were searched during this period (2007-2016), such that the high heterogeneity (50% < I2) in this study was analyzed using the DerSimonian Laird method. Data were categorized into subgroups based on year of study and province. Due to the high validity of the diagnosis of organisms and quantitative results, antimicrobial susceptibility test (AST) was used to detect MRSA. Data analysis was performed using statsdirect software. Results: Based on the available data in medical databases, 678 articles were selected. In total, 29 remaining studies entered the meta-analysis phase. In this study, the overall prevalence of MRSA using MIC is 53% (95% CI: 0.42.31, 63.90); in 2016 it was 77.56% (95% CI: 76.07, 78.99) and in 2007 was 57.49% (95% CI: 53.17, 61.72). The heterogeneity was estimated to be 98.5% (95% CI: 98.4, 98.6). Conclusion: Based on the results, there is an increasing prevalence of MRSA in Iran. These may be due to the failure or lack of infection control activities and antimicrobial selection pressure.https://jmb.tums.ac.ir/index.php/jmb/article/view/329Antimicrobial resistance (AMR)IranMethicillin-resistant Staphylococcus aureusMethicillinMRSAStaphylococcus aureus |
| spellingShingle | Ghobad Moradi Seyyede Maryam Bechashk Nader Esmailnasab Behzad Mohsenpour Rashid Ramazanzadeh Daem Roshani Ebrahim Ghaderi Methicillin-Resistant Staphylococcus aureus Using Broth Micro Dilution Method in Iran: A Meta-Analysis (2007-2016) Journal of Medical Bacteriology Antimicrobial resistance (AMR) Iran Methicillin-resistant Staphylococcus aureus Methicillin MRSA Staphylococcus aureus |
| title | Methicillin-Resistant Staphylococcus aureus Using Broth Micro Dilution Method in Iran: A Meta-Analysis (2007-2016) |
| title_full | Methicillin-Resistant Staphylococcus aureus Using Broth Micro Dilution Method in Iran: A Meta-Analysis (2007-2016) |
| title_fullStr | Methicillin-Resistant Staphylococcus aureus Using Broth Micro Dilution Method in Iran: A Meta-Analysis (2007-2016) |
| title_full_unstemmed | Methicillin-Resistant Staphylococcus aureus Using Broth Micro Dilution Method in Iran: A Meta-Analysis (2007-2016) |
| title_short | Methicillin-Resistant Staphylococcus aureus Using Broth Micro Dilution Method in Iran: A Meta-Analysis (2007-2016) |
| title_sort | methicillin resistant staphylococcus aureus using broth micro dilution method in iran a meta analysis 2007 2016 |
| topic | Antimicrobial resistance (AMR) Iran Methicillin-resistant Staphylococcus aureus Methicillin MRSA Staphylococcus aureus |
| url | https://jmb.tums.ac.ir/index.php/jmb/article/view/329 |
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