Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences
A safe and effective rejuvenation method with few side effects is one of the main purposes of most of the aesthetic procedures. As wound healing process is similar to rejuvenation mechanisms, diverse methods such as ablative and non-ablative laser have been applied to meet this target. A recent meth...
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Format: | Article |
Language: | fas |
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Isfahan University of Medical Sciences
2015-09-01
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Series: | مجله دانشکده پزشکی اصفهان |
Subjects: | |
Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/4763 |
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author | Nioosha Nekooie-Marnany Fariba Jaffary Mohammad Ali Nilforoushzadeh |
author_facet | Nioosha Nekooie-Marnany Fariba Jaffary Mohammad Ali Nilforoushzadeh |
author_sort | Nioosha Nekooie-Marnany |
collection | DOAJ |
description | A safe and effective rejuvenation method with few side effects is one of the main purposes of most of the aesthetic procedures. As wound healing process is similar to rejuvenation mechanisms, diverse methods such as ablative and non-ablative laser have been applied to meet this target. A recent method that has remarkably taken experts' and technicians’ attention is platelet-rich plasma (PRP) injection. This article reviews molecular mechanisms of aging and rejuvenation. It also evaluates clinical documents regarding the effects of platelet-rich plasma in rejuvenation beside its possible side effects. Because of high concentration of growth factors in platelet-rich plasma, it potentially can accelerate wound healing. However, there is a concern about the relation between the high level of growth factors and induction of signaling cascades of tumors. Long-term platelet-rich plasma outcomes need to be more investigated in cohort studies. |
first_indexed | 2024-03-12T08:53:52Z |
format | Article |
id | doaj.art-72ffb6665df04c729d5216fcdb0289e3 |
institution | Directory Open Access Journal |
issn | 1027-7595 1735-854X |
language | fas |
last_indexed | 2024-03-12T08:53:52Z |
publishDate | 2015-09-01 |
publisher | Isfahan University of Medical Sciences |
record_format | Article |
series | مجله دانشکده پزشکی اصفهان |
spelling | doaj.art-72ffb6665df04c729d5216fcdb0289e32023-09-02T16:10:38ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2015-09-0133343116811851952Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse InfluencesNioosha Nekooie-Marnany0Fariba Jaffary1Mohammad Ali Nilforoushzadeh2Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IranProfessor, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan AND Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IranAssociate Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IranA safe and effective rejuvenation method with few side effects is one of the main purposes of most of the aesthetic procedures. As wound healing process is similar to rejuvenation mechanisms, diverse methods such as ablative and non-ablative laser have been applied to meet this target. A recent method that has remarkably taken experts' and technicians’ attention is platelet-rich plasma (PRP) injection. This article reviews molecular mechanisms of aging and rejuvenation. It also evaluates clinical documents regarding the effects of platelet-rich plasma in rejuvenation beside its possible side effects. Because of high concentration of growth factors in platelet-rich plasma, it potentially can accelerate wound healing. However, there is a concern about the relation between the high level of growth factors and induction of signaling cascades of tumors. Long-term platelet-rich plasma outcomes need to be more investigated in cohort studies.http://jims.mui.ac.ir/index.php/jims/article/view/4763Platelet-rich plasmaRejuvenationWound healingGrowth factorsCancer |
spellingShingle | Nioosha Nekooie-Marnany Fariba Jaffary Mohammad Ali Nilforoushzadeh Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences مجله دانشکده پزشکی اصفهان Platelet-rich plasma Rejuvenation Wound healing Growth factors Cancer |
title | Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences |
title_full | Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences |
title_fullStr | Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences |
title_full_unstemmed | Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences |
title_short | Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences |
title_sort | platelet rich plasma prp therapy in skin rejuvenation benefits and adverse influences |
topic | Platelet-rich plasma Rejuvenation Wound healing Growth factors Cancer |
url | http://jims.mui.ac.ir/index.php/jims/article/view/4763 |
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