Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences

A safe and effective rejuvenation method with few side effects is one of the main purposes of most of the aesthetic procedures. As wound healing process is similar to rejuvenation mechanisms, diverse methods such as ablative and non-ablative laser have been applied to meet this target. A recent meth...

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Main Authors: Nioosha Nekooie-Marnany, Fariba Jaffary, Mohammad Ali Nilforoushzadeh
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2015-09-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/4763
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author Nioosha Nekooie-Marnany
Fariba Jaffary
Mohammad Ali Nilforoushzadeh
author_facet Nioosha Nekooie-Marnany
Fariba Jaffary
Mohammad Ali Nilforoushzadeh
author_sort Nioosha Nekooie-Marnany
collection DOAJ
description A safe and effective rejuvenation method with few side effects is one of the main purposes of most of the aesthetic procedures. As wound healing process is similar to rejuvenation mechanisms, diverse methods such as ablative and non-ablative laser have been applied to meet this target. A recent method that has remarkably taken experts' and technicians’ attention is platelet-rich plasma (PRP) injection. This article reviews molecular mechanisms of aging and rejuvenation. It also evaluates clinical documents regarding the effects of platelet-rich plasma in rejuvenation beside its possible side effects. Because of high concentration of growth factors in platelet-rich plasma, it potentially can accelerate wound healing. However, there is a concern about the relation between the high level of growth factors and induction of signaling cascades of tumors. Long-term platelet-rich plasma outcomes need to be more investigated in cohort studies.
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spelling doaj.art-72ffb6665df04c729d5216fcdb0289e32023-09-02T16:10:38ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2015-09-0133343116811851952Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse InfluencesNioosha Nekooie-Marnany0Fariba Jaffary1Mohammad Ali Nilforoushzadeh2Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IranProfessor, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan AND Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IranAssociate Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IranA safe and effective rejuvenation method with few side effects is one of the main purposes of most of the aesthetic procedures. As wound healing process is similar to rejuvenation mechanisms, diverse methods such as ablative and non-ablative laser have been applied to meet this target. A recent method that has remarkably taken experts' and technicians’ attention is platelet-rich plasma (PRP) injection. This article reviews molecular mechanisms of aging and rejuvenation. It also evaluates clinical documents regarding the effects of platelet-rich plasma in rejuvenation beside its possible side effects. Because of high concentration of growth factors in platelet-rich plasma, it potentially can accelerate wound healing. However, there is a concern about the relation between the high level of growth factors and induction of signaling cascades of tumors. Long-term platelet-rich plasma outcomes need to be more investigated in cohort studies.http://jims.mui.ac.ir/index.php/jims/article/view/4763Platelet-rich plasmaRejuvenationWound healingGrowth factorsCancer
spellingShingle Nioosha Nekooie-Marnany
Fariba Jaffary
Mohammad Ali Nilforoushzadeh
Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences
مجله دانشکده پزشکی اصفهان
Platelet-rich plasma
Rejuvenation
Wound healing
Growth factors
Cancer
title Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences
title_full Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences
title_fullStr Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences
title_full_unstemmed Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences
title_short Platelet-Rich Plasma (PRP) Therapy in Skin Rejuvenation: Benefits and Adverse Influences
title_sort platelet rich plasma prp therapy in skin rejuvenation benefits and adverse influences
topic Platelet-rich plasma
Rejuvenation
Wound healing
Growth factors
Cancer
url http://jims.mui.ac.ir/index.php/jims/article/view/4763
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AT faribajaffary plateletrichplasmaprptherapyinskinrejuvenationbenefitsandadverseinfluences
AT mohammadalinilforoushzadeh plateletrichplasmaprptherapyinskinrejuvenationbenefitsandadverseinfluences