Pleural cryobiopsy is useful for comprehensive cancer genetic panel testing
Abstract An 83‐year‐old woman presented with dyspnoea. Her chest X‐ray showed a right‐sided pleural effusion. Flex‐rigid pleuroscopy was performed and showed a mass in the anterior portion. The mass was biopsied with conventional biopsy forceps, but the mass was solid, and sufficient tissues could n...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-07-01
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| Series: | Respirology Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rcr2.581 |
| _version_ | 1819106209885585408 |
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| author | Satoru Ishii Hiromu Watanabe Shinyu Izumi Masayuki Hojo Haruhito Sugiyama |
| author_facet | Satoru Ishii Hiromu Watanabe Shinyu Izumi Masayuki Hojo Haruhito Sugiyama |
| author_sort | Satoru Ishii |
| collection | DOAJ |
| description | Abstract An 83‐year‐old woman presented with dyspnoea. Her chest X‐ray showed a right‐sided pleural effusion. Flex‐rigid pleuroscopy was performed and showed a mass in the anterior portion. The mass was biopsied with conventional biopsy forceps, but the mass was solid, and sufficient tissues could not be obtained. Therefore, the mass was biopsied with a cryoprobe. The tip of the probe was attached to the mass, and it was cooled with carbon dioxide once for 5 sec and then for 7 sec in the same place. The tissue size obtained was 2 mm by conventional biopsy forceps, and 5 mm at 5 sec and 12 mm at 7 sec by cryobiopsy. Histological analysis of the conventional biopsy forceps specimen showed cancer cells in the glandular cavity, but it was not sufficient tissue for comprehensive cancer genetic panel (CGP) testing. The cryobiopsy specimens showed cancer cells and sufficient tissue for comprehensive CGP testing. |
| first_indexed | 2024-12-22T02:34:31Z |
| format | Article |
| id | doaj.art-73013ea43e1841c2b03d6b7316a0b10d |
| institution | Directory Open Access Journal |
| issn | 2051-3380 |
| language | English |
| last_indexed | 2024-12-22T02:34:31Z |
| publishDate | 2020-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Respirology Case Reports |
| spelling | doaj.art-73013ea43e1841c2b03d6b7316a0b10d2022-12-21T18:41:48ZengWileyRespirology Case Reports2051-33802020-07-0185n/an/a10.1002/rcr2.581Pleural cryobiopsy is useful for comprehensive cancer genetic panel testingSatoru Ishii0Hiromu Watanabe1Shinyu Izumi2Masayuki Hojo3Haruhito Sugiyama4Department of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanDepartment of Respiratory Medicine National Center for Global Health and Medicine Tokyo JapanAbstract An 83‐year‐old woman presented with dyspnoea. Her chest X‐ray showed a right‐sided pleural effusion. Flex‐rigid pleuroscopy was performed and showed a mass in the anterior portion. The mass was biopsied with conventional biopsy forceps, but the mass was solid, and sufficient tissues could not be obtained. Therefore, the mass was biopsied with a cryoprobe. The tip of the probe was attached to the mass, and it was cooled with carbon dioxide once for 5 sec and then for 7 sec in the same place. The tissue size obtained was 2 mm by conventional biopsy forceps, and 5 mm at 5 sec and 12 mm at 7 sec by cryobiopsy. Histological analysis of the conventional biopsy forceps specimen showed cancer cells in the glandular cavity, but it was not sufficient tissue for comprehensive cancer genetic panel (CGP) testing. The cryobiopsy specimens showed cancer cells and sufficient tissue for comprehensive CGP testing.https://doi.org/10.1002/rcr2.581Cryobiopsycomprehensive cancer genetic panel testingpleuroscopypleural disease |
| spellingShingle | Satoru Ishii Hiromu Watanabe Shinyu Izumi Masayuki Hojo Haruhito Sugiyama Pleural cryobiopsy is useful for comprehensive cancer genetic panel testing Respirology Case Reports Cryobiopsy comprehensive cancer genetic panel testing pleuroscopy pleural disease |
| title | Pleural cryobiopsy is useful for comprehensive cancer genetic panel testing |
| title_full | Pleural cryobiopsy is useful for comprehensive cancer genetic panel testing |
| title_fullStr | Pleural cryobiopsy is useful for comprehensive cancer genetic panel testing |
| title_full_unstemmed | Pleural cryobiopsy is useful for comprehensive cancer genetic panel testing |
| title_short | Pleural cryobiopsy is useful for comprehensive cancer genetic panel testing |
| title_sort | pleural cryobiopsy is useful for comprehensive cancer genetic panel testing |
| topic | Cryobiopsy comprehensive cancer genetic panel testing pleuroscopy pleural disease |
| url | https://doi.org/10.1002/rcr2.581 |
| work_keys_str_mv | AT satoruishii pleuralcryobiopsyisusefulforcomprehensivecancergeneticpaneltesting AT hiromuwatanabe pleuralcryobiopsyisusefulforcomprehensivecancergeneticpaneltesting AT shinyuizumi pleuralcryobiopsyisusefulforcomprehensivecancergeneticpaneltesting AT masayukihojo pleuralcryobiopsyisusefulforcomprehensivecancergeneticpaneltesting AT haruhitosugiyama pleuralcryobiopsyisusefulforcomprehensivecancergeneticpaneltesting |