Clinical and Prognostic Significance of Cell Sensitivity to Chemotherapy Detected in vitro on Treatment Response and Survival of Leukemia Patients
Multidrug resistance (MDR) is a major challenge in leukemia treatment. The objective of this study was to identity predictors of MDR to allow for rapid and economical assessment of the efficacy of planned antitumor therapy for leukemia patients. The study included 113 patients with acute and chronic...
Main Authors: | Maria Kolesnikova, Aleksandra Sen’kova, Sofia Tairova, Viktor Ovchinnikov, Tatiana Pospelova, Marina Zenkova |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
|
Series: | Journal of Personalized Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-4426/9/2/24 |
Similar Items
-
Effective Prognostic Model for Therapy Response Prediction in Acute Myeloid Leukemia Patients
by: Maria A. Kolesnikova, et al.
Published: (2023-08-01) -
Novel Dicarboximide BK124.1 Breaks Multidrug Resistance and Shows Anticancer Efficacy in Chronic Myeloid Leukemia Preclinical Models and Patients’ CD34<sup>+</sup>/CD38<sup>−</sup> Leukemia Stem Cells
by: Iga Stukan, et al.
Published: (2022-07-01) -
Natural Inhibitors of P-glycoprotein in Acute Myeloid Leukemia
by: Manuela Labbozzetta, et al.
Published: (2023-02-01) -
P-glycoprotein-mediated resistance to chemotherapy in cancer cells: using recombinant cytosolic domains to establish structure-function relationships
by: Di Pietro A., et al.
Published: (1999-01-01) -
Co-Encapsulation of Mitoxantrone and β-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia
by: Kambere Amerigos Daddy J.C., et al.
Published: (2020-02-01)