Internal Mammary Arteries as a Model to Demonstrate Restoration of the Impaired Vasodilation in Hypertension, Using Liposomal Delivery of the CYP1B1 Inhibitor, 2,3′,4,5′-Tetramethoxystilbene

Internal Mammary Arteries as a Model to Demonstrate Restoration of the Impaired Vasodilation in Hypertension, Using Liposomal Delivery of the CYP1B1 Inhibitor, 2,3′,4,5′-Tetramethoxystilbene

A significant number of patients with severe cardiovascular disease, undergoing coronary artery bypass grafting (CABG), present with hypertension. While internal mammary arteries (IMAs) may be a better alternative to vein grafts, their impaired vasodilator function affects their patency. Our objecti...

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Bibliographic Details
Main Authors: Azziza Zaabalawi, Lewis Renshall, Frances Beards, Adam P. Lightfoot, Hans Degens, Yvonne Alexander, Ragheb Hasan, Haris Bilal, Brigitte A. Graf, Lynda K. Harris, May Azzawi
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
2,3′,4,5′-tetramethoxystilbene
endothelial cell
reactive oxygen species
liposomes
oxidative stress
coronary artery
Online Access:https://www.mdpi.com/1999-4923/14/10/2046

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