Diffusion-weighted imaging in the head and neck region: usefulness of apparent diffusion coefficient values for characterization of lesions
PURPOSEWe aimed to evaluate the role of apparent diffusion coefficient (ADC) values calculated from diffusion-weighted imaging for head and neck lesion characterization in daily routine, in comparison with histopathological results.METHODSNinety consecutive patients who underwent magnetic resonance...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2015-05-01
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| Series: | Diagnostic and Interventional Radiology |
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http://www.dirjournal.org/archives/archive-detail/article-preview/diffusion-weighted-imaging-in-the-head-and-neck-re/55802
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| _version_ | 1797691215764783104 |
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| author | İsmail Şerifoğlu İbrahim İlker Oz Murat Damar Özlem Tokgöz Ömer Yazgan Zuhal Erdem |
| author_facet | İsmail Şerifoğlu İbrahim İlker Oz Murat Damar Özlem Tokgöz Ömer Yazgan Zuhal Erdem |
| author_sort | İsmail Şerifoğlu |
| collection | DOAJ |
| description | PURPOSEWe aimed to evaluate the role of apparent diffusion coefficient (ADC) values calculated from diffusion-weighted imaging for head and neck lesion characterization in daily routine, in comparison with histopathological results.METHODSNinety consecutive patients who underwent magnetic resonance imaging (MRI) at a university hospital for diagnosis of neck lesions were included in this prospective study. Diffusion-weighted echo-planar MRI was performed on a 1.5 T unit with b factor of 0 and 1000 s/mm2 and ADC maps were generated. ADC values were measured for benign and malignant whole lesions seen in daily practice.RESULTSThe median ADC value of the malignant tumors and benign lesions were 0.72×10-3 mm2/s, (range, 0.39–1.51×10-3 mm2/s) and 1.17×10-3 mm2/s, (range, 0.52–2.38×10-3 mm2/s), respectively, with a significant difference between them (P < 0.001). A cutoff ADC value of 0.98×10-3 mm2/s was used to distinguish between benign and malignant lesions, yielding 85.3% sensitivity and 78.6% specificity. The median ADC value of lymphomas (0.44×10-3 mm2/s; range, 0.39–0.58×10-3 mm2/s) was significantly smaller (P < 0.001) than that of squamous cell carcinomas (median ADC value 0.72×10-3 mm2/s; range, 0.65–1.06×10-3 mm2/s). There was no significant difference between median ADC values of inflammatory (1.13×10-3 mm2/s; range, 0.85–2.38×10-3 mm2/s) and noninflammatory benign lesions (1.26×10-3 mm2/s; range, 0.52–2.33×10-3 mm2/s).CONCLUSIONDiffusion-weighted imaging and the ADC values can be used to differentiate and characterize benign and malignant head and neck lesions. |
| first_indexed | 2024-03-12T02:10:10Z |
| format | Article |
| id | doaj.art-7309f97254934623840c3ba5f16ccdd3 |
| institution | Directory Open Access Journal |
| issn | 1305-3825 1305-3612 |
| language | English |
| last_indexed | 2024-03-12T02:10:10Z |
| publishDate | 2015-05-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-7309f97254934623840c3ba5f16ccdd32023-09-06T13:48:53ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122015-05-0121320821410.5152/dir.2014.1427913049054Diffusion-weighted imaging in the head and neck region: usefulness of apparent diffusion coefficient values for characterization of lesionsİsmail Şerifoğlu0İbrahim İlker Oz1Murat Damar2Özlem Tokgöz3Ömer Yazgan4Zuhal Erdem5 Department of Radiology, Bulent Ecevit University School of Medicine, Zonguldak, Turkey Department of Radiology, Bulent Ecevit University School of Medicine, Zonguldak, Turkey Department of Radiology, Bulent Ecevit University School of Medicine, Zonguldak, Turkey Department of Radiology, Bulent Ecevit University School of Medicine, Zonguldak, Turkey Department of Head and Neck Surgery, Bulent Ecevit University School of Medicine, Zonguldak, Turkey Department of Radiology, Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey PURPOSEWe aimed to evaluate the role of apparent diffusion coefficient (ADC) values calculated from diffusion-weighted imaging for head and neck lesion characterization in daily routine, in comparison with histopathological results.METHODSNinety consecutive patients who underwent magnetic resonance imaging (MRI) at a university hospital for diagnosis of neck lesions were included in this prospective study. Diffusion-weighted echo-planar MRI was performed on a 1.5 T unit with b factor of 0 and 1000 s/mm2 and ADC maps were generated. ADC values were measured for benign and malignant whole lesions seen in daily practice.RESULTSThe median ADC value of the malignant tumors and benign lesions were 0.72×10-3 mm2/s, (range, 0.39–1.51×10-3 mm2/s) and 1.17×10-3 mm2/s, (range, 0.52–2.38×10-3 mm2/s), respectively, with a significant difference between them (P < 0.001). A cutoff ADC value of 0.98×10-3 mm2/s was used to distinguish between benign and malignant lesions, yielding 85.3% sensitivity and 78.6% specificity. The median ADC value of lymphomas (0.44×10-3 mm2/s; range, 0.39–0.58×10-3 mm2/s) was significantly smaller (P < 0.001) than that of squamous cell carcinomas (median ADC value 0.72×10-3 mm2/s; range, 0.65–1.06×10-3 mm2/s). There was no significant difference between median ADC values of inflammatory (1.13×10-3 mm2/s; range, 0.85–2.38×10-3 mm2/s) and noninflammatory benign lesions (1.26×10-3 mm2/s; range, 0.52–2.33×10-3 mm2/s).CONCLUSIONDiffusion-weighted imaging and the ADC values can be used to differentiate and characterize benign and malignant head and neck lesions. http://www.dirjournal.org/archives/archive-detail/article-preview/diffusion-weighted-imaging-in-the-head-and-neck-re/55802 |
| spellingShingle | İsmail Şerifoğlu İbrahim İlker Oz Murat Damar Özlem Tokgöz Ömer Yazgan Zuhal Erdem Diffusion-weighted imaging in the head and neck region: usefulness of apparent diffusion coefficient values for characterization of lesions Diagnostic and Interventional Radiology |
| title | Diffusion-weighted imaging in the head and neck region: usefulness of apparent diffusion coefficient values for characterization of lesions |
| title_full | Diffusion-weighted imaging in the head and neck region: usefulness of apparent diffusion coefficient values for characterization of lesions |
| title_fullStr | Diffusion-weighted imaging in the head and neck region: usefulness of apparent diffusion coefficient values for characterization of lesions |
| title_full_unstemmed | Diffusion-weighted imaging in the head and neck region: usefulness of apparent diffusion coefficient values for characterization of lesions |
| title_short | Diffusion-weighted imaging in the head and neck region: usefulness of apparent diffusion coefficient values for characterization of lesions |
| title_sort | diffusion weighted imaging in the head and neck region usefulness of apparent diffusion coefficient values for characterization of lesions |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/diffusion-weighted-imaging-in-the-head-and-neck-re/55802
|
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