In vitro adherence of Candida albicans isolated from patients with chronic periodontitis
Adherence is considered an extremely important virulence factor in yeast. OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND METHODS: Candida albicans cells...
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| Format: | Article |
| Language: | English |
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University of São Paulo
2011-08-01
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| Series: | Journal of Applied Oral Science |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000400015 |
| _version_ | 1811212693425618944 |
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| author | Adriana Gadotti Machado Edson Yukio Komiyama Silvana Soléo Ferreira dos Santos Antonio Olavo Cardoso Jorge Fernanda Lourenção Brighenti Cristiane Yumi Koga-Ito |
| author_facet | Adriana Gadotti Machado Edson Yukio Komiyama Silvana Soléo Ferreira dos Santos Antonio Olavo Cardoso Jorge Fernanda Lourenção Brighenti Cristiane Yumi Koga-Ito |
| author_sort | Adriana Gadotti Machado |
| collection | DOAJ |
| description | Adherence is considered an extremely important virulence factor in yeast. OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted. RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000). CONCLUSION:The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis. |
| first_indexed | 2024-04-12T05:33:19Z |
| format | Article |
| id | doaj.art-730fae97a2b340b8805b648f80122315 |
| institution | Directory Open Access Journal |
| issn | 1678-7757 1678-7765 |
| language | English |
| last_indexed | 2024-04-12T05:33:19Z |
| publishDate | 2011-08-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Journal of Applied Oral Science |
| spelling | doaj.art-730fae97a2b340b8805b648f801223152022-12-22T03:45:59ZengUniversity of São PauloJournal of Applied Oral Science1678-77571678-77652011-08-01194384387In vitro adherence of Candida albicans isolated from patients with chronic periodontitisAdriana Gadotti MachadoEdson Yukio KomiyamaSilvana Soléo Ferreira dos SantosAntonio Olavo Cardoso JorgeFernanda Lourenção BrighentiCristiane Yumi Koga-ItoAdherence is considered an extremely important virulence factor in yeast. OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted. RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000). CONCLUSION:The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000400015Candida albicansCell adhesionPeriodontitisVirulence factors |
| spellingShingle | Adriana Gadotti Machado Edson Yukio Komiyama Silvana Soléo Ferreira dos Santos Antonio Olavo Cardoso Jorge Fernanda Lourenção Brighenti Cristiane Yumi Koga-Ito In vitro adherence of Candida albicans isolated from patients with chronic periodontitis Journal of Applied Oral Science Candida albicans Cell adhesion Periodontitis Virulence factors |
| title | In vitro adherence of Candida albicans isolated from patients with chronic periodontitis |
| title_full | In vitro adherence of Candida albicans isolated from patients with chronic periodontitis |
| title_fullStr | In vitro adherence of Candida albicans isolated from patients with chronic periodontitis |
| title_full_unstemmed | In vitro adherence of Candida albicans isolated from patients with chronic periodontitis |
| title_short | In vitro adherence of Candida albicans isolated from patients with chronic periodontitis |
| title_sort | in vitro adherence of candida albicans isolated from patients with chronic periodontitis |
| topic | Candida albicans Cell adhesion Periodontitis Virulence factors |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000400015 |
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