Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions

How testis resident macrophages develop and influence tissue function is not fully understood. Here the authors use mouse lineage tracing methods to document the haematopoietic source, development and recruitment of early testicular macrophages, support of foetal testis differentiation, and interact...

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Bibliographic Details
Main Authors: Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37199-0