Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer’s Disease

The immediate early gene Arc is a master regulator of synaptic function and a critical determinant of memory consolidation. Here, we show that Arc interacts with dynamic chromatin and closely associates with histone markers for active enhancers and transcription in cultured rat hippocampal neurons....

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: How-Wing Leung, Gabriel Foo, Antonius VanDongen
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2022-08-01
Schriftenreihe:Biomedicines
Schlagworte:
Online Zugang:https://www.mdpi.com/2227-9059/10/8/1946