Aerosolized Niosome Formulation Containing Gemcitabine and Cisplatin for Lung Cancer Treatment: Optimization, Characterization and In Vitro Evaluation

Aerosolized Niosome Formulation Containing Gemcitabine and Cisplatin for Lung Cancer Treatment: Optimization, Characterization and In Vitro Evaluation

Gemcitabine (Gem) and cisplatin (Cis) are currently being used for lung cancer treatment, but they are highly toxic in high dosages. This research aimed to develop a niosome formulation containing a low-dosage Gem and Cis (NGC), as an alternative formulation for lung cancer treatment. NGC was prepar...

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Bibliographic Details
Main Authors: Norfatin Izzatie Mohamad Saimi, Norazlinaliza Salim, Noraini Ahmad, Emilia Abdulmalek, Mohd Basyaruddin Abdul Rahman
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
niosome
gemcitabine
cisplatin
heating method
lung cancer
aerosol output
Online Access:https://www.mdpi.com/1999-4923/13/1/59

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