<i>Leishmania</i> and the Model of Predominant Clonal Evolution
As it is the case for other pathogenic microorganisms, the respective impact of clonality and genetic exchange on <i>Leishmania</i> natural populations has been the object of lively debates since the early 1980s. The predominant clonal evolution (PCE) model states that genetic exchange i...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/9/11/2409 |
| Summary: | As it is the case for other pathogenic microorganisms, the respective impact of clonality and genetic exchange on <i>Leishmania</i> natural populations has been the object of lively debates since the early 1980s. The predominant clonal evolution (PCE) model states that genetic exchange in these parasites’ natural populations may have a high relevance on an evolutionary scale, but is not sufficient to erase a persistent phylogenetic signal and the existence of bifurcating trees. Recent data based on high-resolution markers and genomic polymorphisms fully confirm the PCE model down to a microevolutionary level. |
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| ISSN: | 2076-2607 |