Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma

Abstract The treatment outcome of hepatocellular carcinoma (HCC) is severely hampered due to its etiology, and thus in depth understanding of the genetic mechanisms underlying response of HCC to various anticancer agents is needed. Here, we have identified Phosphotyrosine interaction domain-containi...

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Bibliographic Details
Main Authors: Jian Yang, Senlin Li, Jialuo He, Qianqian Xu, Mengyuan Xie, Ci Yang, Hongjie Wang, Yonghui Zhang, Qian Wan, Ming Xiang
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01405-1