Advances in research on the interaction between inflammation and cancer

Inflammation is the body's response to cell damage. Cancer is a general term that describes all malignant tumours. There are no confirmed data on cancer-related inflammation, but some research suggests that up to 50% of cancers may be linked to inflammation, which has led to the concept of ‘can...

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Main Authors: Xin-Da Song, Ya-Ni Wang, Ai-li Zhang, Bin Liu
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060519895347
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author Xin-Da Song
Ya-Ni Wang
Ai-li Zhang
Bin Liu
author_facet Xin-Da Song
Ya-Ni Wang
Ai-li Zhang
Bin Liu
author_sort Xin-Da Song
collection DOAJ
description Inflammation is the body's response to cell damage. Cancer is a general term that describes all malignant tumours. There are no confirmed data on cancer-related inflammation, but some research suggests that up to 50% of cancers may be linked to inflammation, which has led to the concept of ‘cancer-associated inflammation’. Although some cancer patients do not appear to have a chronic inflammatory background, there might be inflammatory cell infiltration in their cancer tissues. The continuation of the inflammatory response plays an important role in the initiation, promotion, malignant transformation, invasion and metastasis of cancer. Anti-inflammatory therapy has been shown to have some effects on the prevention and treatment of cancer, which supports a pathogenic relationship between inflammation and cancer. This review describes the interaction between inflammation and tumour development and the main mechanism of regulation of the inflammatory response during tumour development.
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spelling doaj.art-73171c604a1a48cf9710006f7837f3282022-12-21T18:25:55ZengSAGE PublishingJournal of International Medical Research1473-23002020-10-014810.1177/0300060519895347Advances in research on the interaction between inflammation and cancerXin-Da SongYa-Ni WangAi-li ZhangBin LiuInflammation is the body's response to cell damage. Cancer is a general term that describes all malignant tumours. There are no confirmed data on cancer-related inflammation, but some research suggests that up to 50% of cancers may be linked to inflammation, which has led to the concept of ‘cancer-associated inflammation’. Although some cancer patients do not appear to have a chronic inflammatory background, there might be inflammatory cell infiltration in their cancer tissues. The continuation of the inflammatory response plays an important role in the initiation, promotion, malignant transformation, invasion and metastasis of cancer. Anti-inflammatory therapy has been shown to have some effects on the prevention and treatment of cancer, which supports a pathogenic relationship between inflammation and cancer. This review describes the interaction between inflammation and tumour development and the main mechanism of regulation of the inflammatory response during tumour development.https://doi.org/10.1177/0300060519895347
spellingShingle Xin-Da Song
Ya-Ni Wang
Ai-li Zhang
Bin Liu
Advances in research on the interaction between inflammation and cancer
Journal of International Medical Research
title Advances in research on the interaction between inflammation and cancer
title_full Advances in research on the interaction between inflammation and cancer
title_fullStr Advances in research on the interaction between inflammation and cancer
title_full_unstemmed Advances in research on the interaction between inflammation and cancer
title_short Advances in research on the interaction between inflammation and cancer
title_sort advances in research on the interaction between inflammation and cancer
url https://doi.org/10.1177/0300060519895347
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