Advances in research on the interaction between inflammation and cancer
Inflammation is the body's response to cell damage. Cancer is a general term that describes all malignant tumours. There are no confirmed data on cancer-related inflammation, but some research suggests that up to 50% of cancers may be linked to inflammation, which has led to the concept of ‘can...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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SAGE Publishing
2020-10-01
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Series: | Journal of International Medical Research |
Online Access: | https://doi.org/10.1177/0300060519895347 |
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author | Xin-Da Song Ya-Ni Wang Ai-li Zhang Bin Liu |
author_facet | Xin-Da Song Ya-Ni Wang Ai-li Zhang Bin Liu |
author_sort | Xin-Da Song |
collection | DOAJ |
description | Inflammation is the body's response to cell damage. Cancer is a general term that describes all malignant tumours. There are no confirmed data on cancer-related inflammation, but some research suggests that up to 50% of cancers may be linked to inflammation, which has led to the concept of ‘cancer-associated inflammation’. Although some cancer patients do not appear to have a chronic inflammatory background, there might be inflammatory cell infiltration in their cancer tissues. The continuation of the inflammatory response plays an important role in the initiation, promotion, malignant transformation, invasion and metastasis of cancer. Anti-inflammatory therapy has been shown to have some effects on the prevention and treatment of cancer, which supports a pathogenic relationship between inflammation and cancer. This review describes the interaction between inflammation and tumour development and the main mechanism of regulation of the inflammatory response during tumour development. |
first_indexed | 2024-12-22T12:22:59Z |
format | Article |
id | doaj.art-73171c604a1a48cf9710006f7837f328 |
institution | Directory Open Access Journal |
issn | 1473-2300 |
language | English |
last_indexed | 2024-12-22T12:22:59Z |
publishDate | 2020-10-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Journal of International Medical Research |
spelling | doaj.art-73171c604a1a48cf9710006f7837f3282022-12-21T18:25:55ZengSAGE PublishingJournal of International Medical Research1473-23002020-10-014810.1177/0300060519895347Advances in research on the interaction between inflammation and cancerXin-Da SongYa-Ni WangAi-li ZhangBin LiuInflammation is the body's response to cell damage. Cancer is a general term that describes all malignant tumours. There are no confirmed data on cancer-related inflammation, but some research suggests that up to 50% of cancers may be linked to inflammation, which has led to the concept of ‘cancer-associated inflammation’. Although some cancer patients do not appear to have a chronic inflammatory background, there might be inflammatory cell infiltration in their cancer tissues. The continuation of the inflammatory response plays an important role in the initiation, promotion, malignant transformation, invasion and metastasis of cancer. Anti-inflammatory therapy has been shown to have some effects on the prevention and treatment of cancer, which supports a pathogenic relationship between inflammation and cancer. This review describes the interaction between inflammation and tumour development and the main mechanism of regulation of the inflammatory response during tumour development.https://doi.org/10.1177/0300060519895347 |
spellingShingle | Xin-Da Song Ya-Ni Wang Ai-li Zhang Bin Liu Advances in research on the interaction between inflammation and cancer Journal of International Medical Research |
title | Advances in research on the interaction between inflammation and cancer |
title_full | Advances in research on the interaction between inflammation and cancer |
title_fullStr | Advances in research on the interaction between inflammation and cancer |
title_full_unstemmed | Advances in research on the interaction between inflammation and cancer |
title_short | Advances in research on the interaction between inflammation and cancer |
title_sort | advances in research on the interaction between inflammation and cancer |
url | https://doi.org/10.1177/0300060519895347 |
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