Changes of pancreatic structure in conditions of an acute pancreatitis modelling
Used various variants of 2 models: 1) model with intraperitoneal introduction L-arginin in dozes 3; 4 and 5 g/kg; 2) model with introduction 50 mkl 1 %-s', 2,5 %-s' and 5 %-s' solutions of sodium taurocholat in a channel of a pancreas. Hystologic research and definition of an amylases...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy
2010-01-01
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| Series: | Морфологія |
| Subjects: | |
| Online Access: | http://www.morphology.dp.ua/_pub/MORPHO-2010-04-01/10zdyegp.pdf |
| _version_ | 1811248380363407360 |
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| author | Zinenko D.Yu. Sukhina T.V. |
| author_facet | Zinenko D.Yu. Sukhina T.V. |
| author_sort | Zinenko D.Yu. |
| collection | DOAJ |
| description | Used various variants of 2 models: 1) model with intraperitoneal introduction L-arginin in dozes 3; 4 and 5 g/kg; 2) model with introduction 50 mkl 1 %-s', 2,5 %-s' and 5 %-s' solutions of sodium taurocholat in a channel of a pancreas. Hystologic research and definition of an amylases level in the blood carried out in 1, 4, 8, 12, 24, 48 and 72 hours after an injection. The lead researches on models with intraperitoneal introduction L-arginin and intrachannel introduction of sodium taurocholat have revealed a similar orientation in development of a sharp pancreatitis on dynamics of an amylases level in the blood and on pathomorphological changes of the parenchyma, stroma and microcirculation in the body. For model with introduction of sodium taurocholat in a channel of a pancreas are more characteristic gemorragycal displays alongside with inflammatory and necrotic changes which have an essential gradient from the head to a tail of the gland. It is observed regenerative dynamics of amylase’s concentration in the blood condition, of microvessels and the general tissue structure of a pancreas of comparison with L-аrginin after application of sodium taurocholat. |
| first_indexed | 2024-04-12T15:27:03Z |
| format | Article |
| id | doaj.art-73185cb6d81a47139be73d44eb7e1f35 |
| institution | Directory Open Access Journal |
| issn | 1997-9665 |
| language | Russian |
| last_indexed | 2024-04-12T15:27:03Z |
| publishDate | 2010-01-01 |
| publisher | Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy |
| record_format | Article |
| series | Морфологія |
| spelling | doaj.art-73185cb6d81a47139be73d44eb7e1f352022-12-22T03:27:14ZrusMinistry of Health of Ukraine. Dnipropetrovsk Medical AcademyМорфологія1997-96652010-01-01411721Changes of pancreatic structure in conditions of an acute pancreatitis modellingZinenko D.Yu.Sukhina T.V.Used various variants of 2 models: 1) model with intraperitoneal introduction L-arginin in dozes 3; 4 and 5 g/kg; 2) model with introduction 50 mkl 1 %-s', 2,5 %-s' and 5 %-s' solutions of sodium taurocholat in a channel of a pancreas. Hystologic research and definition of an amylases level in the blood carried out in 1, 4, 8, 12, 24, 48 and 72 hours after an injection. The lead researches on models with intraperitoneal introduction L-arginin and intrachannel introduction of sodium taurocholat have revealed a similar orientation in development of a sharp pancreatitis on dynamics of an amylases level in the blood and on pathomorphological changes of the parenchyma, stroma and microcirculation in the body. For model with introduction of sodium taurocholat in a channel of a pancreas are more characteristic gemorragycal displays alongside with inflammatory and necrotic changes which have an essential gradient from the head to a tail of the gland. It is observed regenerative dynamics of amylase’s concentration in the blood condition, of microvessels and the general tissue structure of a pancreas of comparison with L-аrginin after application of sodium taurocholat.http://www.morphology.dp.ua/_pub/MORPHO-2010-04-01/10zdyegp.pdfpancreasmodels of an acute pancreatitisratmicrocirculationhistostructure |
| spellingShingle | Zinenko D.Yu. Sukhina T.V. Changes of pancreatic structure in conditions of an acute pancreatitis modelling Морфологія pancreas models of an acute pancreatitis rat microcirculation histostructure |
| title | Changes of pancreatic structure in conditions of an acute pancreatitis modelling |
| title_full | Changes of pancreatic structure in conditions of an acute pancreatitis modelling |
| title_fullStr | Changes of pancreatic structure in conditions of an acute pancreatitis modelling |
| title_full_unstemmed | Changes of pancreatic structure in conditions of an acute pancreatitis modelling |
| title_short | Changes of pancreatic structure in conditions of an acute pancreatitis modelling |
| title_sort | changes of pancreatic structure in conditions of an acute pancreatitis modelling |
| topic | pancreas models of an acute pancreatitis rat microcirculation histostructure |
| url | http://www.morphology.dp.ua/_pub/MORPHO-2010-04-01/10zdyegp.pdf |
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