A review on antidepressant activity of omega-3 fatty acids

Background: As per the reports depression will become the major leading cause of disability. Treatment with antidepressants is suboptimal in most of the cases. Studies have shown that Omega 3 fatty acids might play a role in suppression of depression. Objective: This present review summarizes the ro...

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Main Authors: Ravi P Sankar, Durga P S S Devi, Vinay K R Rajan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Archives of Mental Health
Subjects:
Online Access:http://www.amhonline.org/article.asp?issn=2589-9171;year=2015;volume=16;issue=1;spage=22;epage=26;aulast=Sankar;type=0
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author Ravi P Sankar
Durga P S S Devi
Vinay K R Rajan
author_facet Ravi P Sankar
Durga P S S Devi
Vinay K R Rajan
author_sort Ravi P Sankar
collection DOAJ
description Background: As per the reports depression will become the major leading cause of disability. Treatment with antidepressants is suboptimal in most of the cases. Studies have shown that Omega 3 fatty acids might play a role in suppression of depression. Objective: This present review summarizes the role of Omega 3 fatty acids in depression and their efficacy profile. Discussion: As per the reports of World Health Organization, depression will become second leading cause of disability worldwide by 2020. Response to treatment with antidepressants is suboptimal in most of the individuals with depression. From so many years, use of Omega 3 fatty acids, as add on therapy has been research of interest, but till now, no standard decision made on their use in depression. The present review summarizes the role of omega 3 fatty acids in reducing depression, previous clinical studies that evaluated the beneficial effects omega 3fatty acids in prevention and treatment of depressive disorder. Conclusion: By reviewing the previous clinical studies and epidemiological findings, we conclude treatment with omega 3 fatty acids, as an adjuvant to antidepressant medication, may effectively reduce the depressive symptoms.
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spelling doaj.art-73235087dd424384b06f0a354a4857082022-12-21T23:19:25ZengWolters Kluwer Medknow PublicationsArchives of Mental Health2589-91712589-918X2015-01-011612226A review on antidepressant activity of omega-3 fatty acidsRavi P SankarDurga P S S DeviVinay K R RajanBackground: As per the reports depression will become the major leading cause of disability. Treatment with antidepressants is suboptimal in most of the cases. Studies have shown that Omega 3 fatty acids might play a role in suppression of depression. Objective: This present review summarizes the role of Omega 3 fatty acids in depression and their efficacy profile. Discussion: As per the reports of World Health Organization, depression will become second leading cause of disability worldwide by 2020. Response to treatment with antidepressants is suboptimal in most of the individuals with depression. From so many years, use of Omega 3 fatty acids, as add on therapy has been research of interest, but till now, no standard decision made on their use in depression. The present review summarizes the role of omega 3 fatty acids in reducing depression, previous clinical studies that evaluated the beneficial effects omega 3fatty acids in prevention and treatment of depressive disorder. Conclusion: By reviewing the previous clinical studies and epidemiological findings, we conclude treatment with omega 3 fatty acids, as an adjuvant to antidepressant medication, may effectively reduce the depressive symptoms.http://www.amhonline.org/article.asp?issn=2589-9171;year=2015;volume=16;issue=1;spage=22;epage=26;aulast=Sankar;type=0key message: use of omega 3 fatty acids can be considered as an adjuvant therapy with antidepressant treatment that might help to decrease the depressive symptoms. key words: omega-3 fatty acidsdepressionphospholipid polyunsaturated fatty acidsdocosahexaenoic acideicosapentaenoic acid.
spellingShingle Ravi P Sankar
Durga P S S Devi
Vinay K R Rajan
A review on antidepressant activity of omega-3 fatty acids
Archives of Mental Health
key message: use of omega 3 fatty acids can be considered as an adjuvant therapy with antidepressant treatment that might help to decrease the depressive symptoms. key words: omega-3 fatty acids
depression
phospholipid polyunsaturated fatty acids
docosahexaenoic acid
eicosapentaenoic acid.
title A review on antidepressant activity of omega-3 fatty acids
title_full A review on antidepressant activity of omega-3 fatty acids
title_fullStr A review on antidepressant activity of omega-3 fatty acids
title_full_unstemmed A review on antidepressant activity of omega-3 fatty acids
title_short A review on antidepressant activity of omega-3 fatty acids
title_sort review on antidepressant activity of omega 3 fatty acids
topic key message: use of omega 3 fatty acids can be considered as an adjuvant therapy with antidepressant treatment that might help to decrease the depressive symptoms. key words: omega-3 fatty acids
depression
phospholipid polyunsaturated fatty acids
docosahexaenoic acid
eicosapentaenoic acid.
url http://www.amhonline.org/article.asp?issn=2589-9171;year=2015;volume=16;issue=1;spage=22;epage=26;aulast=Sankar;type=0
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