Role of cellular senescence in inflammation and regeneration

Abstract Cellular senescence is the state in which cells undergo irreversible cell cycle arrest and acquire diverse phenotypes. It has been linked to chronic inflammation and fibrosis in various organs as well as to individual aging. Therefore, eliminating senescent cells has emerged as a potential...

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Bibliographic Details
Main Authors: Yuki Saito, Sena Yamamoto, Takako S. Chikenji
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Inflammation and Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s41232-024-00342-5