Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells

Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells

Abstract Glioblastoma cell ability to adapt their functioning to microenvironment changes is a source of the extensive intra-tumor heterogeneity characteristic of this devastating malignant brain tumor. A systemic view of the metabolic pathways underlying glioblastoma cell functioning states is lack...

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Bibliographic Details
Main Authors: Mirca S. Saurty-Seerunghen, Léa Bellenger, Elias A. El-Habr, Virgile Delaunay, Delphine Garnier, Hervé Chneiweiss, Christophe Antoniewski, Ghislaine Morvan-Dubois, Marie-Pierre Junier
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Acta Neuropathologica Communications
Subjects:
Glioma
Computational modeling
scRNA-seq
PUFA
Elongase
Online Access:http://link.springer.com/article/10.1186/s40478-019-0819-y

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