Trend, morbidity profile and immunization status of diphtheria admitted cases: A 5-years review from a sentinel centre in Kolkata

Despite strengthening of the universal immunization program, diphtheria remains endemic in India. Diphtheria is under surveillance for vaccine-preventable diseases of the World Health Organization and also in India. The present record-based retrospective study was conducted on 241 confirmed diphther...

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Main Authors: Samir Kumar Ray, Baisakhi Maji, Anima Haldar, Baijayanti Baur
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Indian Journal of Public Health
Subjects:
Online Access:http://www.ijph.in/article.asp?issn=0019-557X;year=2021;volume=65;issue=1;spage=60;epage=63;aulast=Ray
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author Samir Kumar Ray
Baisakhi Maji
Anima Haldar
Baijayanti Baur
author_facet Samir Kumar Ray
Baisakhi Maji
Anima Haldar
Baijayanti Baur
author_sort Samir Kumar Ray
collection DOAJ
description Despite strengthening of the universal immunization program, diphtheria remains endemic in India. Diphtheria is under surveillance for vaccine-preventable diseases of the World Health Organization and also in India. The present record-based retrospective study was conducted on 241 confirmed diphtheria patients admitted in an infectious disease hospital of Kolkata over 5 years (2015–2019) with the objectives of assessing the admission trend, immunization status, and outcome of patients. Among the patients, majority (57.3%) were female; 50.6% were ≥15 years; 49.0% resided in rural areas. Five-year admission rate did not show any declining trend. Major number of cases occurred in 2016; another peak observed in 2019. Only 27.4% fully immunized rest either partiality immunized (44.4%) or nonimmunized (28.2%). Overall, 54% of the patients developed any complications, and case fatality was 9.5%. Gradual age shift toward adults reiterated the widespread use of adult immunization with Td vaccines. Early reporting to the hospital is necessary to reduce complications and case fatality.
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spelling doaj.art-73338d2467c54bcfa89e377f704d7a712022-12-21T19:52:44ZengWolters Kluwer Medknow PublicationsIndian Journal of Public Health0019-557X2021-01-01651606310.4103/ijph.IJPH_148_20Trend, morbidity profile and immunization status of diphtheria admitted cases: A 5-years review from a sentinel centre in KolkataSamir Kumar RayBaisakhi MajiAnima HaldarBaijayanti BaurDespite strengthening of the universal immunization program, diphtheria remains endemic in India. Diphtheria is under surveillance for vaccine-preventable diseases of the World Health Organization and also in India. The present record-based retrospective study was conducted on 241 confirmed diphtheria patients admitted in an infectious disease hospital of Kolkata over 5 years (2015–2019) with the objectives of assessing the admission trend, immunization status, and outcome of patients. Among the patients, majority (57.3%) were female; 50.6% were ≥15 years; 49.0% resided in rural areas. Five-year admission rate did not show any declining trend. Major number of cases occurred in 2016; another peak observed in 2019. Only 27.4% fully immunized rest either partiality immunized (44.4%) or nonimmunized (28.2%). Overall, 54% of the patients developed any complications, and case fatality was 9.5%. Gradual age shift toward adults reiterated the widespread use of adult immunization with Td vaccines. Early reporting to the hospital is necessary to reduce complications and case fatality.http://www.ijph.in/article.asp?issn=0019-557X;year=2021;volume=65;issue=1;spage=60;epage=63;aulast=Raycase fatality ratecomplicationdiphtheriaimmunizationtrend
spellingShingle Samir Kumar Ray
Baisakhi Maji
Anima Haldar
Baijayanti Baur
Trend, morbidity profile and immunization status of diphtheria admitted cases: A 5-years review from a sentinel centre in Kolkata
Indian Journal of Public Health
case fatality rate
complication
diphtheria
immunization
trend
title Trend, morbidity profile and immunization status of diphtheria admitted cases: A 5-years review from a sentinel centre in Kolkata
title_full Trend, morbidity profile and immunization status of diphtheria admitted cases: A 5-years review from a sentinel centre in Kolkata
title_fullStr Trend, morbidity profile and immunization status of diphtheria admitted cases: A 5-years review from a sentinel centre in Kolkata
title_full_unstemmed Trend, morbidity profile and immunization status of diphtheria admitted cases: A 5-years review from a sentinel centre in Kolkata
title_short Trend, morbidity profile and immunization status of diphtheria admitted cases: A 5-years review from a sentinel centre in Kolkata
title_sort trend morbidity profile and immunization status of diphtheria admitted cases a 5 years review from a sentinel centre in kolkata
topic case fatality rate
complication
diphtheria
immunization
trend
url http://www.ijph.in/article.asp?issn=0019-557X;year=2021;volume=65;issue=1;spage=60;epage=63;aulast=Ray
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