Highly specific and sensitive detection of Burkholderia pseudomallei genomic DNA by CRISPR-Cas12a

Highly specific and sensitive detection of Burkholderia pseudomallei genomic DNA by CRISPR-Cas12a

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Detection of Burkholderia pseudomallei, a causative bacterium for melioidosis, remains a challenging undertaking due to long assay time, laboratory requirements, and the lack of specificity and sensitivity of many current assays. In this study, we are presenting a novel method that circumvents those...

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Bibliographic Details
Main Authors: Somsakul Pop Wongpalee, Hathairat Thananchai, Claire Chewapreecha, Henrik B. Roslund, Chalita Chomkatekaew, Warunya Tananupak, Phumrapee Boonklang, Sukritpong Pakdeerat, Rathanin Seng, Narisara Chantratita, Piyawan Takarn, Phadungkiat Khamnoi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423629/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423629/?tool=EBI

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