Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study
Abstract Background Sepsis remains a major cause of mortality in critical care, for which specific treatments are lacking. The dysregulated response to infection seen in sepsis includes features of lymphocyte dysfunction and exhaustion, suggesting that immune-stimulatory therapy may improve outcomes...
Main Authors: | Julie K. Wilson, Yuan Zhao, Mervyn Singer, Jo Spencer, Manu Shankar-Hari |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-04-01
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Series: | Critical Care |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13054-018-2020-2 |
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