GABA signaling and neuroactive steroids in adrenal medullary chromaffin cells

GABA signaling and neuroactive steroids in adrenal medullary chromaffin cells

GABA is produced not only in the brain, but also in endocrine cells by the two isoforms of glutamic acid decarboxylase (GAD), GAD65 and GAD67. In rat adrenal medullary chromaffin cells only GAD67 is expressed, and GABA is stored in large dense core vesicles, but not synaptic-like microvesicles. The...

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Bibliographic Details
Main Authors: Keita eHarada, Hidetada eMatsuoka, Hiroaki eFujiwara, Yoichi eUeta, Yuchio eYanagawa, Masumi eInoue
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
GABA
GABAA receptors
GAD67
paracrine
neuroactive steroid
PC12 cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00100/full

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