Seroprevalence of HBsAg, Anti-HIV1/2 and Anti-HCV in Pregnancies at Ege University Medical Faculty Hospital
Introduction: Vertical transmission is an important route for hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections in children. Determination of these viral infectious agents during pregnancy is important for both maternal and infant health. In this stud...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bilimsel Tip Yayinevi
2017-09-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2017-22-03-120-125.pdf |
| Summary: | Introduction: Vertical transmission is an important route for hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections in children. Determination of these viral infectious agents during pregnancy is important for both maternal and infant health. In this study, the prevalances of hepatitis B surface antigen (HBsAg), hepatitis C antibody (anti-HCV) and human immunodeficiency virus antibody (anti-HIV1/2) were determined in pregnant women admitted to Ege University Medical Faculty Hospital outpatient pregnancy clinic.
Materials and Methods: Test records of pregnant women, aged between 16-49 years (mean 30.3 ± 5.9), who applied to Ege University Medical Faculty Hospital Obstetrics Outpatient Clinic between January 2014 and July 2017 were tested for HBsAg, anti-HCV and anti-HIV in the Virology Laboratory, and were evaluated. Samples were screened for viral markers using Architect i2000SR (Abbott, USA).
Results: ELISA results demonstrated the existence of HBsAg in 127 (1.4%) among 8967; anti-HCV in 34 (0.4%) among 8865 and
anti-HIV 1/2 in 12 (0.1%) among 8803 pregnant women.
Conclusion: Since perinatal exposure is an important mode of HBV transmission resulting in chronic disease in infected infants and is preventable with immunoprophylaxis, it is important to determine the HBV infected mother. The same is true for HIV infection which can be prevented if it is detected during pregnancy. For HCV infection, even though definite effective preventive measures are lacking, invasive obstetric procedures favoring the contact with contaminated maternal blood could be avoided. Screening of these viral infectious agents during pregnancy is important for both maternal and infant health. |
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| ISSN: | 1300-932X 1300-932X |