| Summary: | Objective:This epidemiological
study was conducted in the
joint haematology-orthopaedics
clinic of a university hospital. The aim was to analyse the
data in terms of age and radiology of
patients with moderate
or severe haemophilia A and knee involvement. Materials and Method:This was a retrospective study
49 patients with knee problems out of 130 haemophilia A and
musculoskeletal problems.
Kellgren-Lawrence (KL) classification was used for
radiological assessments of osteoarthritis degree. Results:KL degree was 3 or 4 for most patients (27/39,
69.23%) in the group. There was statistically a meaningful correlation between
KL degree and patients’ age (Spearman’s: rs
= 0.512, p = 0.001). There were 7 patients with KL degree
4 at the age of 50 or younger (14.29%). 25 patients in 49(51.02%)
had total knee arthroplasty(TKA) and 10(40%) of those was bilateral. Mean age for bilateral
TKA(56.35) was
higher than unilateral(49.87). There was a statistically meaningful
correlation between patient age and the patients with
TKA (Spearman’s: rs
= 0.338, p = 0.017).
There were 2 revision surgeries out of 35 TKA (5.71%).
Most of the patients had prophylactic factor treatment (43,
87.75%). Conclusion:
Our study signify the high ratio of bilateral
knee replacements in haemophilia A patients and how early age they progressed
to KL stage 4 comparing to normal population. These results show the importance
of patient care in this group of patients, close follow-up and prophylactic
treatment. They should be managed in experienced centres by an experience team
to decrease the risks and complications.
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